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DIPROPYLENE GLYCOL

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Endocrine disruption (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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foundation282 products
conditioner245 products
mask209 products
facial moisturizer/treatment93 products
antiperspirant/deodorant87 products
bar soap80 products
antiperspirant/deodorant (men's)79 products
concealer75 products
hair treatment/serum63 products
serums & essences61 products
facial cleanser59 products
daily use with SPF37 products
moisturizer36 products
body wash/cleanser35 products
around-eye cream30 products
shampoo28 products
toners/astringents26 products
21 products
lipstick20 products
eye shadow20 products
exfoliant/scrub19 products
brow liner18 products
makeup primer17 products
setting powder/spray15 products
CC cream15 products
body spray14 products
sunless tanning13 products
BB cream12 products
recreational sunscreen12 products
hair styling aide11 products
hair color and bleaching10 products
eye makeup remover10 products
fragrance for women10 products
fragrance for men9 products
makeup remover8 products
bronzer/highlighter8 products
eye liner8 products
anti-aging7 products
detangler7 products
hand cream7 products
mascara6 products
lip gloss6 products
body firming lotion6 products
styling mousse/foam5 products
lip balm5 products
bubble bath5 products
liquid hand soap5 products
hair spray5 products
glitter4 products
bath oil/salts/soak4 products
facial powder3 products
styling gel/lotion3 products
beard care3 products
nail polish2 products
blush2 products
lip plumper2 products
hand sanitizer1 products
after sun product1 products
nail treatment1 products
skin fading/lightener1 products
baby wipes1 products
baby bubble bath1 products
foot cleansing1 products
baby soap1 products
foot moisturizer1 products
baby lotion1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Human any irritant - strong evidenceCosmetic Ingredient Review Assessments
Limited evidence of any irritationOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
Limited evidence of any toxicityOpen scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of any toxicityOpen scientific literature
Associated with any toxicityOpen scientific literature
One or more animal studies show any effects at high doses (low dose studies may be unavailable for this ingredient)Open scientific literature
Classified as a low human health priorityEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
any - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Associated with immunotoxicity or allergiesOpen scientific literature

Endocrine disruption

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Concern Reference
Associated with endocrine disruptionOpen scientific literature

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
73 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
  • This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.

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