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Data: Fair

Diethyl Phthalate

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Endocrine disruption (low), Non-reproductive organ system toxicity (low), and Ecotoxicology (low)

SYNONYMS

1,2-BENZENEDICARBOXYLIC ACID, DIETHYL ESTER, 1,2BENZENEDICARBOXYLIC ACID, DIETHYL ESTER, DEP, DIETHYL 1,2-BENZENEDICARBOXYLATE, DIETHYL ESTER 1,2-BENZENEDICARBOXYLIC ACID, DIETHYL PHTHALATE, and DIETHYLPHTHALATE

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Diethyl Phthalate is an aromatic diester of ethyl alcohol and phthalic acid.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • MODERATE
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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Developmental/reproductive toxicity

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CONCERN REFERENCE
Limited evidence of reproductive toxicityNational Library of Medicine HazMap

Endocrine disruption

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CONCERN REFERENCE
Limited evidence of any disruptionOpen scientific literature
Associated with endocrine disruptionOpen scientific literature

Allergies/immunotoxicity

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CONCERN REFERENCE
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Categorized List of Inert Pesticide Ingredients
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Ecotoxicology

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CONCERN REFERENCE
Wildlife and environmental toxicityEPA Clean Water Act - Priority Pollutants
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
2983 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Open scientific/peer reviewed literature
  • EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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