Other ConcernsEndocrine disruption (low), Non-reproductive organ system toxicity (low), and Ecotoxicology (low)
SYNONYMS1,2-BENZENEDICARBOXYLIC ACID, DIETHYL ESTER, 1,2BENZENEDICARBOXYLIC ACID, DIETHYL ESTER, DEP, DIETHYL 1,2-BENZENEDICARBOXYLATE, DIETHYL ESTER 1,2-BENZENEDICARBOXYLIC ACID, DIETHYL PHTHALATE, and DIETHYLPHTHALATE
Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation
Diethyl Phthalate is an aromatic diester of ethyl alcohol and phthalic acid.
See how this product scores for common concerns.
LOWAllergies & Immunotoxicity
MODERATEDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|Limited evidence of reproductive toxicity||National Library of Medicine HazMap|
|Limited evidence of any disruption||Open scientific literature|
|Associated with endocrine disruption||Open scientific literature|
|Limited evidence of immune system toxicity or allergies||National Library of Medicine HazMap|
Organ system toxicity (non-reproductive)
|One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Categorized List of Inert Pesticide Ingredients|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|Classified as a low human health priority||Environment Canada Domestic Substance List|
|reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study||National Library of Medicine HazMap|
|Wildlife and environmental toxicity||EPA Clean Water Act - Priority Pollutants|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||Cosmetic Ingredient Review Assessments|
|Safety assessment was based on related chemical||Cosmetic Ingredient Review Assessments|
|2983 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Cosmetic Ingredient Review Assessments|
Persistence and bioaccumulation
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- Open scientific/peer reviewed literature
- EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.