Menu
DIBUTYL PHTHALATE
Score:
Data: Robust
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high), Endocrine disruption (moderate), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (high), and Ecotoxicology (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
Use restrictions
| Concern | Reference |
|---|---|
| Violation of government restrictions - Banned or found unsafe for use in cosmetics | CosIng |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Known human respiratory toxicant | EPA Hazardous Air Pollutants |
| One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Categorized List of Inert Pesticide Ingredients |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
| Classified as a low human health priority | Environment Canada Domestic Substance List |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Endocrine disruption
| Concern | Reference |
|---|---|
| Human endocrine disruptor - strong evidence | European Commission on Endocrine Disruption |
| Limited evidence of endocrine disruption | Scorecard.org Toxicity Information |
| endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | Our Stolen Future Endocrine Disruptors |
| endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | Illinois EPA Chemicals Associated with Endocrine System |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Possible human developmental toxicant | California EPA Proposition 65 |
| Limited evidence of reproductive toxicity | CPS&Q - Classification & Labelling |
| Limited evidence of reproductive toxicity | National Library of Medicine HazMap |
| Limited evidence of developmental toxicity | Scorecard.org Toxicity Information |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Persistent, bioaccumulative in wildlife | OSPAR PBTs - Substances of Possible Concern |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
| Not suspected to be persistent | Environment Canada Domestic Substance List |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Limited evidence of immune system toxicity or allergies | National Library of Medicine HazMap |
Ecotoxicology
| Concern | Reference |
|---|---|
| Wildlife and environmental toxicity | EPA Clean Water Act - Priority Pollutants |
| Wildlife and environmental toxicity | CPS&Q - Classification & Labelling |
| Wildlife and environmental toxicity | Illinois EPA Chemicals Associated with Endocrine System |
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| Insufficient data to determine safety | EPA Integrated Risk Information System (IRIS) |
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments |
| 13018 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Cancer
| Concern | Reference |
|---|---|
| Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | EPA Integrated Risk Information System (IRIS) |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Cosmetic Ingredient Review Assessments |
Data Sources
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
- EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- Colborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
- Illinois EPA (Illinois Environmental Protection Agency). 2000. Preliminary list of chemicals associated with endocrine system effects in animals and humans (*) or in vitro (+). In EPA (U.S. Environmental Protection Agency) 2000. Handbook for Non-Cancer Health Effects Valuation, Appendix C.
- California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- OSPAR (Oslo-Paris). 2002. OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
- EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
