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DIAZOLIDINYL UREA (FORMALDEHYDE RELEASER)

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low) and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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conditioner57 products
shampoo46 products
hair styling aide40 products
moisturizer38 products
lipstick34 products
styling gel/lotion34 products
hair treatment/serum25 products
body firming lotion22 products
mask22 products
after sun product21 products
facial moisturizer/treatment12 products
foot moisturizer12 products
concealer11 products
body wash/cleanser10 products
exfoliant/scrub10 products
foundation10 products
styling mousse/foam9 products
daily use with SPF8 products
facial cleanser8 products
hand cream8 products
recreational sunscreen7 products
hair spray7 products
facial powder5 products
toners/astringents5 products
detangler4 products
anti-aging4 products
glitter3 products
mascara3 products
CC cream3 products
shaving cream3 products
around-eye cream2 products
serums & essences2 products
eye makeup remover2 products
skin fading/lightener2 products
after shave2 products
baby sunscreen2 products
makeup remover2 products
eye liner2 products
brow liner2 products
damaged skin treatment2 products
2 products
sunless tanning2 products
BB cream1 products
other eye makeup1 products
foot cleansing1 products
fragrance for women1 products
antiperspirant/deodorant (men's)1 products
bar soap1 products
nail polish1 products
tanning oil1 products
shaving cream (men's)1 products
makeup primer1 products
muscle/joint soreness1 products
bronzer/highlighter1 products

Contamination concerns

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Chemical
FORMALDEHYDE

Allergies/immunotoxicity

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Concern Reference
Known human any toxicant or allergenFormaldehyde - Global Harmonized System (GHS)
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Human skin toxicant or allergen - strong evidenceFormaldehyde - Global Harmonized System (GHS) Hazard Codes
Human any toxicant or allergen - strong evidenceDe Groot AC 2010. Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Contact Dermatitis, 62: 2–17.
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Cancer

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Concern Reference
Cancer - limited evidenceIARC (International Agency for Research on Cancer) 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99.

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments
The total content of formaldehyde in the finished cosmetic product must not exceed 0.2%Scientific Committee on Cosmetic Products and Non-Food Products (SCCPNP) 2002. OPINION CONCERNING A CLARIFICATION ON THE FORMALDEHYDE AND PARA-FORMALDEHYDE ENTRY IN DIRECTIVE 76/768/EEC ON COSMETIC PRODUCTS.

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
58 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Formaldehyde - Global Harmonized System (GHS)
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Formaldehyde - Global Harmonized System (GHS) Hazard Codes
  • De Groot AC 2010. Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Contact Dermatitis, 62: 2–17.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • IARC (International Agency for Research on Cancer) 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99.
  • Scientific Committee on Cosmetic Products and Non-Food Products (SCCPNP) 2002. OPINION CONCERNING A CLARIFICATION ON THE FORMALDEHYDE AND PARA-FORMALDEHYDE ENTRY IN DIRECTIVE 76/768/EEC ON COSMETIC PRODUCTS.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

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