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DECYL GLUCOSIDE

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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shampoo309 products
body wash/cleanser239 products
facial cleanser204 products
liquid hand soap198 products
baby shampoo77 products
concealer58 products
exfoliant/scrub58 products
baby soap58 products
makeup remover54 products
hair color and bleaching39 products
baby wipes34 products
bubble bath23 products
baby bubble bath23 products
facial moisturizer/treatment23 products
mask23 products
bar soap19 products
conditioner17 products
beard cleanser15 products
recreational sunscreen12 products
serums & essences9 products
daily use with SPF8 products
8 products
sunless tanning8 products
setting powder/spray6 products
moisturizer6 products
styling mousse/foam6 products
eye makeup remover5 products
toners/astringents5 products
shaving cream5 products
makeup primer5 products
toothpaste4 products
hair styling aide4 products
hair treatment/serum3 products
body firming lotion3 products
bath oil/salts/soak3 products
foot cleansing2 products
foundation2 products
beard care2 products
lip gloss2 products
hand sanitizer2 products
anti-aging2 products
foot moisturizer2 products
around-eye cream1 products
body oil1 products
vapor rubs1 products
hair-loss treatment1 products
baby toothpaste1 products
eye liner1 products
lipstick1 products
shaving cream (men's)1 products
bronzer/highlighter1 products
body spray1 products
baby lotion1 products
oil controller1 products
hand cream1 products
fragrance for women1 products
fragrance for men1 products

Allergies/immunotoxicity

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Concern Reference
Allergic contact dermatitis reported in human case studies.L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology.
Human patch testing shows that incidence of alkyl glucoside-induced allergic dermatitis is relatively high.Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290.
A review of industry studies indicates alkyl polyglucosides are not dermal sensitizers.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Developmental/reproductive toxicity

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Concern Reference
A review of industry studies notes reduced testis and accessory sex gland weight in an animal studyAndreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
A review of industry studies indicates alkyl polyglucosides are not reproductive or developmental toxicants.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53;
This substance causes severe skin burns and eye damage and causes serious eye damage.European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6

Organ system toxicity (non-reproductive)

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Concern Reference
This substance may be fatal if swallowed and enters airways.European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 32 (S3): 22-48, 2013

Cancer

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Concern Reference
A review of industry studies indicates alkyl polyglucosides are not mutagenic.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Data gaps

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Concern Reference
25 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology.
  • Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290.
  • Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
  • Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53;
  • European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6
  • IJT 32 (S3): 22-48, 2013
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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