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DECYL GLUCOSIDE
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (low), Endocrine disruption (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| shampoo | 194 products |
| body wash/cleanser | 152 products |
| liquid hand soap | 107 products |
| facial cleanser | 103 products |
| concealer | 58 products |
| baby shampoo | 44 products |
| baby soap | 34 products |
| makeup remover | 32 products |
| exfoliant/scrub | 29 products |
| hair color and bleaching | 26 products |
| baby bubble bath | 17 products |
| bubble bath | 17 products |
| mask | 15 products |
| facial moisturizer/treatment | 14 products |
| conditioner | 12 products |
| baby wipes | 12 products |
| beach & sport sunscreen | 10 products |
| bar soap | 9 products |
| serums & essences | 9 products |
| beard cleanser | 8 products |
| sunless tanning | 6 products |
| moisturizer | 5 products |
| moisturizer with SPF | 5 products |
| shaving cream | 4 products |
| anti-aging | 4 products |
| makeup primer | 4 products |
| bath oil/salts/soak | 3 products |
| hair styling aide | 3 products |
| eye makeup remover | 3 products |
| foot cleansing | 2 products |
| styling mousse/foam | 2 products |
| hand sanitizer | 2 products |
| hair treatment/serum | 2 products |
| 2 products | |
| fragrance for men | 1 products |
| hand cream | 1 products |
| beard care | 1 products |
| around-eye cream | 1 products |
| styling gel/lotion | 1 products |
| eye liner | 1 products |
| body oil | 1 products |
| other men's products | 1 products |
| vapor rubs | 1 products |
| fragrance for women | 1 products |
| foot moisturizer | 1 products |
| foundation | 1 products |
| toners/astringents | 1 products |
| baby lotion | 1 products |
| lipstick | 1 products |
| body firming lotion | 1 products |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Allergic contact dermatitis reported in human case studies. | L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology. |
| Human patch testing shows that incidence of alkyl glucoside-induced allergic dermatitis is relatively high. | Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290. |
| A review of industry studies indicates alkyl polyglucosides are not dermal sensitizers. | Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker. |
Endocrine disruption
| Concern | Reference |
|---|---|
| A review of industry studies notes reduced prostate weight only at low doses in one animal study. | Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker. |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| A review of industry studies notes reduced testis and accessory sex gland weight in an animal study | Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker. |
| A review of industry studies indicates alkyl polyglucosides are not reproductive or developmental toxicants. | Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker. |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Safe for use when formulated to be non-irritating | Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53; |
| This substance causes severe skin burns and eye damage and causes serious eye damage. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6 |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| This substance may be fatal if swallowed and enters airways. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6 |
Use restrictions
| Concern | Reference |
|---|---|
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 32 (S3): 22-48, 2013 |
Cancer
| Concern | Reference |
|---|---|
| A review of industry studies indicates alkyl polyglucosides are not mutagenic. | Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker. |
Data gaps
| Concern | Reference |
|---|---|
| 25 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Data Sources
- L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology.
- Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290.
- Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
- Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
- Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53;
- European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6
- IJT 32 (S3): 22-48, 2013
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
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