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DECYL GLUCOSIDE

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low), Endocrine disruption (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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shampoo194 products
body wash/cleanser152 products
liquid hand soap107 products
facial cleanser103 products
concealer58 products
baby shampoo44 products
baby soap34 products
makeup remover32 products
exfoliant/scrub29 products
hair color and bleaching26 products
baby bubble bath17 products
bubble bath17 products
mask15 products
facial moisturizer/treatment14 products
conditioner12 products
baby wipes12 products
beach & sport sunscreen10 products
bar soap9 products
serums & essences9 products
beard cleanser8 products
sunless tanning6 products
moisturizer5 products
moisturizer with SPF5 products
shaving cream4 products
anti-aging4 products
makeup primer4 products
bath oil/salts/soak3 products
hair styling aide3 products
eye makeup remover3 products
foot cleansing2 products
styling mousse/foam2 products
hand sanitizer2 products
hair treatment/serum2 products
2 products
fragrance for men1 products
hand cream1 products
beard care1 products
around-eye cream1 products
styling gel/lotion1 products
eye liner1 products
body oil1 products
other men's products1 products
vapor rubs1 products
fragrance for women1 products
foot moisturizer1 products
foundation1 products
toners/astringents1 products
baby lotion1 products
lipstick1 products
body firming lotion1 products

Allergies/immunotoxicity

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Concern Reference
Allergic contact dermatitis reported in human case studies.L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology.
Human patch testing shows that incidence of alkyl glucoside-induced allergic dermatitis is relatively high.Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290.
A review of industry studies indicates alkyl polyglucosides are not dermal sensitizers.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Endocrine disruption

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Concern Reference
A review of industry studies notes reduced prostate weight only at low doses in one animal study.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Developmental/reproductive toxicity

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Concern Reference
A review of industry studies notes reduced testis and accessory sex gland weight in an animal studyAndreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
A review of industry studies indicates alkyl polyglucosides are not reproductive or developmental toxicants.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53;
This substance causes severe skin burns and eye damage and causes serious eye damage.European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6

Organ system toxicity (non-reproductive)

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Concern Reference
This substance may be fatal if swallowed and enters airways.European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 32 (S3): 22-48, 2013

Cancer

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Concern Reference
A review of industry studies indicates alkyl polyglucosides are not mutagenic.Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.

Data gaps

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Concern Reference
25 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • L F. Soriano, M. Wilkinson, D. A. Thompson, N. M. Stone, R. A. Sabroe, E. Nic Dhonncha, A. Mughal, G. A. Johnston, C. R. Holden, A. Havelin, C. Green, S. A. Ghaffar, P. Divekar, P. Cousen, M. U. Chowdhury, C. G. Bertram & D. A. Buckley. 2020. Prevalence of allergic contact dermatitis to decyl and lauryl glucoside in the UK and Ireland. The British journal of dermatology.
  • Bevin Bhoyrul, Lea Solman, Stephen Kirk, David Orton & Mark Wilkinson 2019. Patch testing with alkyl glucosides: Concomitant reactions are common but not ubiquitous. Contact dermatitis 80(5), 286-290.
  • Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
  • Andreas Willing, Horst Messinger & Walter Aulmann 2004. Ecology and Toxicology of Alkyl Polyglycosides. New York: Marcel Dekker.
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3144; Chemical_Name: Decyl Glucoside; ; ; Classification: QQQ02, QQQ53;
  • European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: ; cas_numbers: 54549-25-6
  • IJT 32 (S3): 22-48, 2013
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

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