Other Concerns
Use restrictions (high) and Contamination concerns (high)SYNONYMS
Unacceptable
Unacceptable: EWG VERIFIED products cannot contain this ingredient
In industrial production of colorants, the term 'lake' is applied to pigments or dyes that are precipitated with metal salts such as aluminum, calcium, barium, or others. Most lake pigments are synthetically produced from coal tar or petroleum.
Common concerns
See how this product scores for common concerns.
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MODERATECancer
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LOWAllergies & Immunotoxicity
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LOWDevelopmental and Reproductive Toxicity
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HIGHUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
lipstick | 563 products |
lip gloss | 159 products |
lip balm | 48 products |
nail polish | 39 products |
blush | 16 products |
lip liner | 15 products |
eye shadow | 12 products |
glitter | 11 products |
bronzer/highlighter | 10 products |
lip plumper | 8 products |
lip balm with SPF | 4 products |
4 products | |
mask | 2 products |
body spray | 1 products |
makeup primer | 1 products |
eye liner | 1 products |
hair color and bleaching | 1 products |
body art | 1 products |
Contamination concerns
Chemical |
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BIPHENYL-2-YLAMINE |
Use restrictions
CONCERN | REFERENCE |
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Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any | Open scientific literature |
Determined safe for use in cosmetics, subject to concentration or use limitations - any | FDA Color Additive Status |
Cancer
CONCERN | REFERENCE |
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Limited evidence of carcinogenicity | Open scientific literature |
Not likely to be mutagenic in humans | Open scientific literature |
Not likely to be carcinogenic in humans | Open scientific literature |
Organ system toxicity (non-reproductive)
CONCERN | REFERENCE |
---|---|
Limited evidence of any toxicity | Scorecard.org Toxicity Information |
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Allergies/immunotoxicity
CONCERN | REFERENCE |
---|---|
One or more animal studies show any or allergenic effects at moderate doses | Open scientific literature |
Informational
CONCERN | REFERENCE |
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Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives Lakes - Batch Certified by the U.S. Food and Drug Administration | CTFA International Cosmetic Ingredient Dictionary and Handbook |
Data gaps
CONCERN | REFERENCE |
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5 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Developmental/reproductive toxicity
CONCERN | REFERENCE |
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Not likely to be a any toxicant in humans | Open scientific literature |
Ecotoxicology
CONCERN | REFERENCE |
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Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
CONCERN | REFERENCE |
---|---|
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
- Open scientific/peer reviewed literature
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.