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Data: Limited

D&C Red No. 33 (Ci 17200)

  • This ingredient's score is higher if used in products intended for use around the eyes due to increased risk of absorption. The score is lower if used in products not intended for use around the eyes.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high) and Contamination concerns (high)

SYNONYMS

● 2,7-NAPHTHALENEDISULFONI C ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-, DISODIUM SALT
● 2,7NAPHTHALENEDISULFONIC ACID, 5AMINO4HYDROXY3(PHENYLAZO), DISODIUM SALT
● 5-AMINO-4-HYDROXY-3-(PHENYLAZO)- DISODIUM SALT 2,7-NAPHTHALENEDISULFONI C ACID
● CI 17200
● D&C RED 33
● D&C RED NO. 33
● D&C RED NO. 33 (CI 17200)
● DISODIUM 5-AMINO-4-HYDROXY-3-(PHENYLAZO)NAPHTHALENE-2,7-DISULPHONATE
● DISODIUM SALT 2,7-NAPHTHALENEDISULFONI C ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-
● FD&C RED 33
● RED 33

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient


D&C Red 33 is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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body wash/cleanser284 products
liquid hand soap217 products
shampoo152 products
bath oil/salts/soak125 products
conditioner116 products
lipstick86 products
fragrance for women62 products
exfoliant/scrub51 products
body spray39 products
sunless tanning39 products
lip gloss38 products
bar soap37 products
moisturizer35 products
lip balm29 products
facial cleanser27 products
mask26 products
hair treatment/serum26 products
hair styling aide26 products
blush22 products
bubble bath19 products
mouthwash17 products
eye liner17 products
polish remover14 products
hand sanitizer14 products
fragrance for men13 products
facial moisturizer/treatment13 products
styling gel/lotion12 products
shaving cream10 products
serums & essences8 products
eye shadow8 products
hair color and bleaching7 products
toners/astringents6 products
hand cream6 products
nail polish5 products
hair spray5 products
lip liner5 products
baby bubble bath5 products
5 products
around-eye cream4 products
makeup primer4 products
daily use with SPF4 products
foot moisturizer3 products
nail treatment3 products
antiperspirant/deodorant (men's)3 products
foundation3 products
antiperspirant/deodorant2 products
baby lotion2 products
body firming lotion2 products
toothpaste2 products
styling mousse/foam2 products
brow liner2 products
baby shampoo2 products
setting powder/spray2 products
nail glue2 products
baby soap1 products
tooth whitening1 products
detangler1 products
after shave1 products
shaving cream (men's)1 products
after sun product1 products
recreational sunscreen1 products
concealer1 products
tanning oil1 products
depilatory1 products

Contamination concerns

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Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmeticsFDA Color Additive Status

Cancer

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CONCERN REFERENCE
Limited evidence of carcinogenicityOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature

Allergies/immunotoxicity

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CONCERN REFERENCE
One or more animal studies show any or allergenic effects at moderate dosesOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Developmental/reproductive toxicity

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CONCERN REFERENCE
Not likely to be a any toxicant in humansOpen scientific literature

Data gaps

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CONCERN REFERENCE
47 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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