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HOW WE DETERMINE SCORES Learn more About EWG VERIFIED™

Data: Limited

D&C Red No. 33 (Ci 17200)

  • This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high) and Contamination concerns (high)

SYNONYMS

2,7-NAPHTHALENEDISULFONI C ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-, DISODIUM SALT, 2,7NAPHTHALENEDISULFONIC ACID, 5AMINO4HYDROXY3(PHENYLAZO), DISODIUM SALT, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)- DISODIUM SALT 2,7-NAPHTHALENEDISULFONI C ACID, CI 17200, D&C RED 33, D&C RED NO. 33, D&C RED NO. 33 (CI 17200), DISODIUM 5-AMINO-4-HYDROXY-3-(PHENYLAZO)NAPHTHALENE-2,7-DISULPHONATE, DISODIUM SALT 2,7-NAPHTHALENEDISULFONI C ACID, 5-AMINO-4-HYDROXY-3-(PHENYLAZO)-, FD&C RED 33, and RED 33

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

D&C Red 33 is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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body wash/cleanser273 products
liquid hand soap241 products
shampoo131 products
bath oil/salts/soak125 products
lipstick103 products
conditioner86 products
fragrance for women85 products
exfoliant/scrub44 products
bar soap43 products
hand sanitizer39 products
mask35 products
body spray32 products
sunless tanning32 products
facial cleanser28 products
lip gloss27 products
lip balm25 products
bubble bath23 products
hair styling aide21 products
fragrance for men20 products
moisturizer19 products
hair treatment/serum19 products
eye liner18 products
brow liner16 products
mouthwash15 products
facial moisturizer/treatment15 products
styling gel/lotion14 products
blush13 products
polish remover12 products
shaving cream12 products
serums & essences8 products
eye shadow8 products
foot moisturizer6 products
baby bubble bath6 products
hair color and bleaching6 products
makeup primer6 products
daily use with SPF6 products
toners/astringents5 products
body firming lotion5 products
hand cream5 products
nail polish4 products
recreational sunscreen4 products
bronzer/highlighter3 products
antiperspirant/deodorant2 products
around-eye cream2 products
baby lotion2 products
hair spray2 products
nail treatment2 products
styling mousse/foam2 products
shaving cream (men's)2 products
lip plumper2 products
after sun product2 products
2 products
setting powder/spray2 products
baby soap1 products
toothpaste1 products
eye makeup remover1 products
hair relaxer1 products
baby shampoo1 products
foundation1 products
body art1 products
lip balm with SPF1 products

Contamination concerns

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Chemical
BIPHENYL-2-YLAMINE

Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmeticsFDA Color Additive Status

Cancer

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CONCERN REFERENCE
Limited evidence of carcinogenicityOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature

Allergies/immunotoxicity

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CONCERN REFERENCE
One or more animal studies show any or allergenic effects at moderate dosesOpen scientific literature

Data gaps

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CONCERN REFERENCE
47 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive not approved by FDA for cosmetics used around eyesFDA Color Additive Status

Developmental/reproductive toxicity

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CONCERN REFERENCE
Not likely to be a any toxicant in humansOpen scientific literature
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • Open scientific/peer reviewed literature
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend
WEIGHT-OF-EVIDENCE APPROACH

A product’s hazard score is not an average of the ingredients’ hazard scores. It is calculated using a weight-of-evidence approach that factors in all of the hazards or health impacts associated with the ingredients.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability
NONE

Ingredients have not been assessed.

LIMITED-FAIR

There is only a modest volume of research.

GOOD-ROBUST

Ingredients have been studied extensively.

Can’t find your product?

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