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D&C Red No. 33 (CI 17200)
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high) and Contamination concerns (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| body wash/cleanser | 351 products |
| liquid hand soap | 257 products |
| lipstick | 206 products |
| shampoo | 166 products |
| conditioner | 127 products |
| bath oil/salts/soak | 123 products |
| fragrance for women | 72 products |
| bar soap | 72 products |
| lip gloss | 59 products |
| exfoliant/scrub | 43 products |
| body spray | 41 products |
| bubble bath | 40 products |
| hand sanitizer | 37 products |
| mask | 36 products |
| hair styling aide | 31 products |
| facial cleanser | 29 products |
| moisturizer | 27 products |
| fragrance for men | 24 products |
| lip balm | 22 products |
| sunless tanning | 22 products |
| hair treatment/serum | 21 products |
| mouthwash | 21 products |
| styling gel/lotion | 20 products |
| facial moisturizer/treatment | 19 products |
| brow liner | 15 products |
| blush | 13 products |
| makeup primer | 10 products |
| hair color and bleaching | 10 products |
| shaving cream | 10 products |
| baby lotion | 8 products |
| foundation | 8 products |
| polish remover | 8 products |
| serums & essences | 7 products |
| daily use with SPF | 6 products |
| foot moisturizer | 6 products |
| baby bubble bath | 6 products |
| bronzer/highlighter | 6 products |
| body firming lotion | 5 products |
| antiperspirant/deodorant | 5 products |
| nail polish | 5 products |
| toothpaste | 5 products |
| toners/astringents | 5 products |
| foot cleansing | 4 products |
| after sun product | 4 products |
| recreational sunscreen | 4 products |
| detangler | 3 products |
| hand cream | 3 products |
| lip plumper | 2 products |
| baby shampoo | 2 products |
| makeup remover | 2 products |
| eye liner | 2 products |
| hair spray | 2 products |
| nail treatment | 2 products |
| hair-loss treatment | 2 products |
| setting powder/spray | 2 products |
| hair relaxer | 2 products |
| shaving cream (men's) | 2 products |
| 2 products | |
| damaged skin treatment | 1 products |
| beard care | 1 products |
| BB cream | 1 products |
| body art | 1 products |
| lip balm with SPF | 1 products |
| antiperspirant/deodorant (men's) | 1 products |
| baby soap | 1 products |
| styling mousse/foam | 1 products |
| glitter | 1 products |
| eye makeup remover | 1 products |
| around-eye cream | 1 products |
| anti-aging | 1 products |
Contamination concerns
| Chemical |
|---|
| BIPHENYL-2-YLAMINE |
Use restrictions
| Concern | Reference |
|---|---|
| Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes | FDA Color Additive Status |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics | FDA Color Additive Status |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| One or more animal studies show any or allergenic effects at moderate doses | Open scientific literature |
Data gaps
| Concern | Reference |
|---|---|
| 47 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration | CTFA International Cosmetic Ingredient Dictionary and Handbook |
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive not approved by FDA for cosmetics used around eyes | FDA Color Additive Status |
Cancer
| Concern | Reference |
|---|---|
| Not likely to be mutagenic in humans | Open scientific literature |
| Not likely to be carcinogenic in humans | Open scientific literature |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Not likely to be a any toxicant in humans | Open scientific literature |
Data Sources
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- Open scientific/peer reviewed literature
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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