D&C Red No. 33 (Ci 17200)
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
Other Concerns
Use restrictions (high) and Contamination concerns (high)SYNONYMS
Unacceptable
Unacceptable: EWG VERIFIED products cannot contain this ingredient
D&C Red 33 is a synthetic dye produced from petroleum or coal tar sources; this dye is FDA-approved for use in pharmaceuticals and cosmetics.
Common concerns
See how this product scores for common concerns.
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MODERATECancer
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LOWAllergies & Immunotoxicity
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LOWDevelopmental and Reproductive Toxicity
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HIGHUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
body wash/cleanser | 297 products |
liquid hand soap | 226 products |
shampoo | 158 products |
bath oil/salts/soak | 127 products |
conditioner | 114 products |
lipstick | 83 products |
fragrance for women | 68 products |
exfoliant/scrub | 50 products |
lip gloss | 38 products |
sunless tanning | 38 products |
bar soap | 37 products |
moisturizer | 35 products |
body spray | 30 products |
facial cleanser | 29 products |
lip balm | 29 products |
hair styling aide | 28 products |
mask | 27 products |
hair treatment/serum | 27 products |
hand sanitizer | 25 products |
bubble bath | 22 products |
blush | 22 products |
eye liner | 17 products |
mouthwash | 16 products |
fragrance for men | 13 products |
facial moisturizer/treatment | 13 products |
polish remover | 13 products |
styling gel/lotion | 11 products |
shaving cream | 10 products |
serums & essences | 8 products |
eye shadow | 8 products |
toners/astringents | 7 products |
hair color and bleaching | 7 products |
baby bubble bath | 6 products |
hand cream | 6 products |
nail polish | 5 products |
hair spray | 5 products |
lip liner | 5 products |
5 products | |
around-eye cream | 4 products |
makeup primer | 4 products |
foot moisturizer | 3 products |
nail treatment | 3 products |
antiperspirant/deodorant (men's) | 3 products |
brow liner | 3 products |
daily use with SPF | 3 products |
foundation | 3 products |
antiperspirant/deodorant | 2 products |
baby lotion | 2 products |
body firming lotion | 2 products |
styling mousse/foam | 2 products |
baby shampoo | 2 products |
setting powder/spray | 2 products |
nail glue | 2 products |
baby soap | 1 products |
tooth whitening | 1 products |
toothpaste | 1 products |
detangler | 1 products |
after shave | 1 products |
shaving cream (men's) | 1 products |
after sun product | 1 products |
recreational sunscreen | 1 products |
concealer | 1 products |
tanning oil | 1 products |
depilatory | 1 products |
Contamination concerns
Chemical |
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BIPHENYL-2-YLAMINE |
Use restrictions
CONCERN | REFERENCE |
---|---|
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes | FDA Color Additive Status |
Determined safe for use in cosmetics, subject to concentration or use limitations - Color additive approved by FDA for limited uses in cosmetics | FDA Color Additive Status |
Cancer
CONCERN | REFERENCE |
---|---|
Limited evidence of carcinogenicity | Open scientific literature |
Not likely to be mutagenic in humans | Open scientific literature |
Not likely to be carcinogenic in humans | Open scientific literature |
Allergies/immunotoxicity
CONCERN | REFERENCE |
---|---|
One or more animal studies show any or allergenic effects at moderate doses | Open scientific literature |
Ecotoxicology
CONCERN | REFERENCE |
---|---|
Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Informational
CONCERN | REFERENCE |
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Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive not approved by FDA for cosmetics used around eyes | FDA Color Additive Status |
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration | CTFA International Cosmetic Ingredient Dictionary and Handbook |
Organ system toxicity (non-reproductive)
CONCERN | REFERENCE |
---|---|
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
CONCERN | REFERENCE |
---|---|
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Developmental/reproductive toxicity
CONCERN | REFERENCE |
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Not likely to be a any toxicant in humans | Open scientific literature |
Data gaps
CONCERN | REFERENCE |
---|---|
47 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- Open scientific/peer reviewed literature
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.