CI 45410 (D&C Red No. 27 or 28) Lake
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|lip gloss||640 products|
|lip balm||356 products|
|lip liner||218 products|
|lip plumper||44 products|
|eye shadow||34 products|
|lip balm with SPF||33 products|
|bath oil/salts/soak||19 products|
|facial powder||17 products|
|nail polish||11 products|
|setting powder/spray||11 products|
|eye liner||9 products|
|hair color and bleaching||7 products|
|makeup primer||5 products|
|body oil||1 products|
|makeup remover||1 products|
|oil controller||1 products|
|fragrance for men||1 products|
|BB cream||1 products|
|body powder||1 products|
|Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any||Open scientific literature|
|Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes||FDA Color Additive Status|
|Determined safe for use in cosmetics, subject to concentration or use limitations - any||FDA Color Additive Status|
Persistence and bioaccumulation
|Persistent, bioaccumulative in wildlife||Open scientific literature|
Organ system toxicity (non-reproductive)
|Classified as expected to be toxic or harmful||Open scientific literature|
|Limited evidence of any toxicity||Scorecard.org Toxicity Information|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Irritation (skin, eyes, or lungs)
|Limited evidence of eye irritation||Open scientific literature|
|One or more animal studies show any irritation at high doses||Open scientific literature|
|Cancer - weight of evidence unknown/unassessed||Open scientific literature|
|any - weight of evidence unknown/unassessed||Open scientific literature|
|Suspected to be an environmental toxin and be persistent or bioaccumulative||Open scientific literature|
|Wildlife and environmental toxicity||Open scientific literature|
|Suspected to be an environmental toxin||Open scientific literature|
|Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)||Environment Canada Domestic Substance List|
|Uncertain environmental toxin and uncertain persistent or bioaccumulative||Environment Canada Domestic Substance List|
|Associated with endocrine disruption||Open scientific literature|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives Lakes - Batch Certified by the U.S. Food and Drug Administration||CTFA International Cosmetic Ingredient Dictionary and Handbook|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Open scientific literature|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics||FDA Color Additive Status|
|0 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
- Open scientific/peer reviewed literature
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer