D&C RED 27
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|eye liner||70 products|
|lip balm||19 products|
|bath oil/salts/soak||18 products|
|lip gloss||11 products|
|lip balm with SPF||7 products|
|hair color and bleaching||2 products|
|bar soap||1 products|
|shaving cream||1 products|
|Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive not approved by FDA for cosmetics used around eyes||FDA Color Additive Status|
Persistence and bioaccumulation
|Persistent, bioaccumulative in wildlife||Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)|
Organ system toxicity (non-reproductive)
|Classified as expected to be toxic or harmful||Environment Canada Domestic Substance List|
Irritation (skin, eyes, or lungs)
|Limited evidence of eye irritation||European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website|
|Irritating to the rabbit eye.||Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Acid Red 92.|
|Increased incidence of pituitary tumors in mice. Mutagenicity observed in a bacerial cell assay but not mammalian tests (in vitro or in vivo).||Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Acid Red 92.|
|Limited evidence of teratogenicity in dietary exposure studies in mice.||Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Acid Red 92.|
|Suspected to be an environmental toxin and be persistent or bioaccumulative||Environment Canada Domestic Substance List|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Wildlife and environmental toxicity||European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website|
|Modeling suggests this substance may interact with the androgen receptor.||National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 13473-26-2; Chemical_Name: AKA218|
|110 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics||FDA Color Additive Status|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration||CTFA International Cosmetic Ingredient Dictionary and Handbook|
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website
- Scientific Committee on Consumer Safety (SCCS) 2012. Opinion on Acid Red 92.
- National Toxicology Program (NTP) 2020. EWG Toxcast Analysis. Appears as: CAS: 13473-26-2; Chemical_Name: AKA218
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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