EWG Skin Deep® | What is CYANOCOBALAMIN (VITAMIN B12)

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED®

Data: Fair

Cyanocobalamin (Vitamin B12)

IMAGE SOURCE: PubChem

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Other Concerns

SYNONYMS

● 1H-BENZIMIDAZOLE, 5,6-DIMETHYL-1-(3-O-PHOSPHONO-A -D-RIBOFURANOSYL)-, MONOESTER WITH COBINAMIDE

● 5,6-DIMETHYL-1-(3-O-PHOSPHONO-A -D-RIBOFURANOSYL)- MONOESTER WITH COBINAMIDE 1H-BENZIMIDAZOLE

● CYANIDE, INNER SALT

● CYANOCOBALAMIN

● CYANOCOBALAMIN (VITAMIN B12)

● INNER SALT CYANIDE

● MONOESTER WITH COBINAMIDE 1H-BENZIMIDAZOLE, 5,6-DIMETHYL-1-(3-O-PHOSPHONO-A -D-RIBOFURANOSYL)-

● VITAMIN B12

This ingredient is not currently on EWG's Skin Deep Restricted or Unacceptable Lists.

According to the Office of Dietary Supplements of the National Institutes of Health, naturally occurring vitamin B12 exists in several forms and contains the mineral cobalt, so compounds with vitamin B12 activity are collectively called 'cobalamins'. Cyanocobalamin is a synthetic form of vitamin B12 most commonly found in dietary supplements and prescription medications. Once ingested, cyanocobalamin is converted in the body into active forms of Vitamin B12.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
LOW

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

facial moisturizer/treatment	17 products
mask	9 products
serums & essences	8 products
toners/astringents	6 products
shampoo	6 products
moisturizer	3 products
facial cleanser	3 products
conditioner	3 products
styling gel/lotion	2 products
around-eye cream	2 products
exfoliant/scrub	2 products
toothpaste	1 products
	1 products
body wash/cleanser	1 products
hair styling aide	1 products
bar soap	1 products
body spray	1 products
nail treatment	1 products
other eye makeup	1 products
setting powder/spray	1 products
shaving cream	1 products
hair-loss treatment	1 products
facial cleansing wipes	1 products

Data gaps

CONCERN	REFERENCE
30274 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Persistence and bioaccumulation

CONCERN	REFERENCE
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Multiple, additive exposure sources

CONCERN	REFERENCE
Designated as safe for general or specific, limited use in food	FDA Everything Added to Food
Designated as safe for general or specific, limited use in food	FDA Food Additive Status

NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED^® mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability