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COUMARIN

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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fragrance for women111 products
shampoo106 products
conditioner102 products
hair treatment/serum94 products
moisturizer85 products
fragrance for men69 products
body wash/cleanser67 products
hair styling aide65 products
foundation40 products
hair spray33 products
body firming lotion33 products
mask32 products
facial moisturizer/treatment29 products
hand cream29 products
styling gel/lotion24 products
sunless tanning21 products
body spray20 products
liquid hand soap19 products
antiperspirant/deodorant18 products
bar soap18 products
body oil17 products
bath oil/salts/soak17 products
hair color and bleaching16 products
bronzer/highlighter16 products
serums & essences16 products
antiperspirant/deodorant (men's)15 products
facial cleanser15 products
daily use with SPF15 products
detangler14 products
eye shadow13 products
styling mousse/foam10 products
lipstick10 products
after shave9 products
exfoliant/scrub9 products
9 products
concealer8 products
recreational sunscreen7 products
baby shampoo6 products
beard oil6 products
shaving cream (men's)5 products
toners/astringents5 products
anti-aging4 products
shaving cream4 products
hand sanitizer4 products
baby lotion4 products
beard care4 products
foot moisturizer3 products
blush3 products
makeup remover2 products
tanning oil2 products
facial powder2 products
after sun product2 products
lip balm2 products
bubble bath2 products
baby soap2 products
makeup primer2 products
muscle/joint soreness2 products
diaper cream2 products
foot cleansing2 products
cuticle treatment1 products
lip plumper1 products
lip gloss1 products
around-eye cream1 products
body powder1 products
eyelash glue1 products
hair relaxer1 products
baby oil1 products
setting powder/spray1 products

Allergies/immunotoxicity

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Concern Reference
Known human immune system toxicant or allergenSCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
Limited evidence of [[system]] toxicity or allergiesEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Coumarin; 2H-chromen-2-one; (2H)-1-Benzopyran-2-one; -; - chromen-2-one; 1,2-benzopyran-2-one; 1,2-benzopyrone; 1-Benzopyran-2-one; 2H Chromen-2-one; 2H-1-Benzopyran-2-on; 2H-1-Benzopyran-2-one; 2H-Chromen-2-one; Chromen-2-one; COUMARIN; Coumarin; 2H-; cas_numbers: 91-64-5

Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Restricted in cosmetics - labeling requirement for allergensCosIng

Cancer

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Concern Reference
Cancer - limited evidenceCarcinogenic Potency Database http://potency.berkeley.edu/app14.html Environmental Defense reviewed this compilation of results on carcinogenicity in rats and mice covering 1298 chemicals and added any chemical with positive results in at least two species by a relevant route of exposure to its list of suspect carcinogens.
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 77;2000

Miscellaneous

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Concern Reference
Prohibited for use in foodFDA Food Additive Status

Data gaps

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Concern Reference
8313 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - The substance was formerly approved as a food additive but is now banned; there may be some toxicology data available.FDA Everything Added to Food

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Coumarin; 2H-chromen-2-one; (2H)-1-Benzopyran-2-one; -; - chromen-2-one; 1,2-benzopyran-2-one; 1,2-benzopyrone; 1-Benzopyran-2-one; 2H Chromen-2-one; 2H-1-Benzopyran-2-on; 2H-1-Benzopyran-2-one; 2H-Chromen-2-one; Chromen-2-one; COUMARIN; Coumarin; 2H-; cas_numbers: 91-64-5
  • IFRA 1/2020
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • Carcinogenic Potency Database http://potency.berkeley.edu/app14.html Environmental Defense reviewed this compilation of results on carcinogenicity in rats and mice covering 1298 chemicals and added any chemical with positive results in at least two species by a relevant route of exposure to its list of suspect carcinogens.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 77;2000
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

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