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COUMARIN

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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fragrance for women66 products
moisturizer47 products
shampoo40 products
body wash/cleanser35 products
foundation31 products
conditioner24 products
fragrance for men17 products
hair treatment/serum15 products
eye shadow13 products
mask12 products
facial moisturizer/treatment11 products
bath oil/salts/soak11 products
lipstick10 products
hair styling aide10 products
hand cream10 products
styling gel/lotion9 products
bronzer/highlighter9 products
body spray8 products
facial cleanser8 products
serums & essences7 products
moisturizer with SPF7 products
antiperspirant/deodorant7 products
liquid hand soap7 products
detangler6 products
sunless tanning5 products
bar soap5 products
body oil4 products
beach & sport sunscreen4 products
hair spray4 products
body firming lotion4 products
blush3 products
beard oil3 products
exfoliant/scrub3 products
shaving cream3 products
toners/astringents3 products
styling mousse/foam3 products
baby soap2 products
baby lotion2 products
makeup primer2 products
hair color and bleaching2 products
after shave2 products
after sun product2 products
baby shampoo2 products
diaper cream1 products
vapor rubs1 products
anti-aging1 products
makeup remover1 products
bubble bath1 products
lip balm1 products
around-eye cream1 products
antiperspirant/deodorant (men's)1 products
hair relaxer1 products

Allergies/immunotoxicity

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Concern Reference
Known human immune system toxicant or allergenSCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA_Standard_212html

Cancer

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Concern Reference
Cancer - limited evidenceCarcinogenic Potency Database http://potency.berkeley.edu/app14.html Environmental Defense reviewed this compilation of results on carcinogenicity in rats and mice covering 1298 chemicals and added any chemical with positive results in at least two species by a relevant route of exposure to its list of suspect carcinogens.
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 77;2000

Miscellaneous

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Concern Reference
Prohibited for use in foodFDA Food Additive Status

Data gaps

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Concern Reference
8313 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - The substance was formerly approved as a food additive but is now banned; there may be some toxicology data available.FDA Everything Added to Food

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • IFRA_Standard_212html
  • Carcinogenic Potency Database http://potency.berkeley.edu/app14.html Environmental Defense reviewed this compilation of results on carcinogenicity in rats and mice covering 1298 chemicals and added any chemical with positive results in at least two species by a relevant route of exposure to its list of suspect carcinogens.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 77;2000
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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