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Data: Good

Cocamidopropyl Betaine

  • This ingredient’s score is higher if used in products that will not be immediately rinsed off due to increased risk of absorption.
  • Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

Other Concerns

Use restrictions (high) and Contamination concerns (high)

SYNONYMS

● 1-PROPANAMINIUM, 3-AMINO-N-(CARBOXYMETHYL)-N,N-DIMETHYL-, N-COCO ACYL DERIVS., INNER SALTS
● 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-, HYDROXIDE, INNER SALT
● 1PROPANAMINIUM, 3AMINON(CARBOXYMETHYL)N,NDIMETHYL, NCOCO ACYL DERIVS., HYDROXIDES, INNER SALTS
● CADG
● COCAMIDO BETAINE
● COCAMIDOPROPYL BETAINE
● COCAMIDOPROPYL DIMETHYL GLYCINE
● COCOAMIDOPROPYL BETAINE
● COCOYL AMIDE PROPYLBETAINE
● COCOYL AMIDE PROPYLDI METHYL GLYCINE SOLUTION
● COCOYL AMIDE PROPYLDIMETHYL GLYCINE
● HYDROXIDE INNER SALT 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-
● HYDROXIDES INNER QUATERNARY AMMONIUM COMPOUNDS, (CARBOXYMETHYL)(3-COCOAMIDOPROPYL)DIMETHYL
● INNER QUATERNARY AMMONIUM COMPOUNDS, (CARBOXYMETHYL)(3-COCOAMIDOPROPYL)DIMETHYL, HYDROXIDES
● INNER SALT 1-PROPANAMINIUM, N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-, HYDROXIDE
● INNER SALT N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-1-PROPANAMINIUM HYDROXIDE
● N-(CARBOXYMETHYL)-N,N-DIMETHYL-3-[(1-OXOCOCONUT)AMINO]-1-PROPANAMINIUM HYDROXIDE, INNER SALT
● N-COCAMIDOPROPYL-N,N-DIMETHYLGLYCINE, HYDROXIDE, INNER SALT; COCOAMIDOPROPYLBETAINE; N-(COCOAMIDOPROPYL)-N,N-DIMETHYL-N-CARBOXYMETHYL AMMONIUM, BETAINE; N-(3-COCOAMIDOPROPYL)-N,N-DIMETHYL-N-CARBOXYMET
● SALTS

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Cocamidopropyl betaine is a surfactant; it has been associated with irritation and allergic contact dermatitis, reactions that could be due to the ingredient itself or to impurities present in it, such as 3-dimethylaminopropylamine.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
shampoo1609 products
body wash/cleanser1237 products
liquid hand soap771 products
facial cleanser438 products
conditioner251 products
toothpaste233 products
exfoliant/scrub139 products
bubble bath116 products
baby shampoo87 products
hair color and bleaching63 products
baby soap63 products
bath oil/salts/soak52 products
bar soap51 products
styling mousse/foam44 products
hair treatment/serum41 products
mask34 products
beard cleanser29 products
hair styling aide17 products
makeup remover13 products
baby bubble bath13 products
12 products
sunless tanning11 products
moisturizer11 products
tooth whitening10 products
shaving cream9 products
beard care7 products
detangler6 products
foot cleansing6 products
hair spray6 products
baby wipes6 products
hair-loss treatment6 products
anti-aging5 products
eye liner5 products
facial moisturizer/treatment4 products
styling gel/lotion4 products
baby lotion4 products
shaving cream (men's)3 products
antiperspirant/deodorant (men's)3 products
hand sanitizer2 products
baby toothpaste2 products
glitter2 products
after sun product2 products
facial cleansing wipes2 products
body cleansing wipes2 products
mouthwash1 products
oil controller1 products
eye makeup remover1 products
hair relaxer1 products
toners/astringents1 products
hand cream1 products
antiperspirant/deodorant1 products
daily use with SPF1 products
vapor rubs1 products
baby sunscreen1 products
setting powder/spray1 products
damaged skin treatment1 products
serums & essences1 products
makeup primer1 products
around-eye cream1 products

Contamination concerns

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Use restrictions

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CONCERN REFERENCE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Unsafe in products left on skin and not rinsed offCosmetic Ingredient Review Assessments
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - anyOpen scientific literature
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Allergies/immunotoxicity

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CONCERN REFERENCE
Limited evidence of sensitization toxicity or allergiesOpen scientific literature
any or allergies - weight of evidence unknown/unassessedOpen scientific literature

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Unsafe in products left on skin and not rinsed offCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
73236 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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September 23, 2023 | Los Angeles, CA

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