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CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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bath oil/salts/soak29 products
toners/astringents22 products
toothpaste21 products
lip gloss18 products
antiperspirant/deodorant16 products
mask15 products
facial moisturizer/treatment14 products
body wash/cleanser12 products
moisturizer12 products
lipstick11 products
facial cleanser11 products
exfoliant/scrub7 products
shampoo6 products
mouthwash6 products
mascara5 products
conditioner5 products
serums & essences4 products
antiperspirant/deodorant (men's)4 products
after shave4 products
around-eye cream4 products
fragrance for women3 products
hand cream3 products
anti-aging3 products
liquid hand soap3 products
blush2 products
baby wipes2 products
hair styling aide2 products
eye liner2 products
makeup primer2 products
makeup remover2 products
hair treatment/serum2 products
beach & sport sunscreen2 products
baby toothpaste2 products
baby soap1 products
tooth whitening1 products
baby shampoo1 products
baby sunscreen1 products
cuticle treatment1 products
eye shadow1 products
styling gel/lotion1 products
beard oil1 products

Contamination concerns

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Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsFinal report 12/2016 available from CIR

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Allergies/immunotoxicity

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Concern Reference
Limited evidence of [[system]] toxicity or allergiesEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
Safe for use when formulated to be non-sensitizingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Data gaps

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Concern Reference
111 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • IFRA 1/2020
  • Final report 12/2016 available from CIR
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
  • Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

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