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CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT

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Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms

  • Use restrictions (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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bath oil/salts/soak29 products
toners/astringents22 products
toothpaste21 products
lip gloss18 products
antiperspirant/deodorant16 products
mask15 products
facial moisturizer/treatment14 products
body wash/cleanser12 products
moisturizer12 products
lipstick11 products
facial cleanser11 products
exfoliant/scrub7 products
shampoo6 products
mouthwash6 products
mascara5 products
conditioner5 products
serums & essences4 products
antiperspirant/deodorant (men's)4 products
after shave4 products
around-eye cream4 products
fragrance for women3 products
hand cream3 products
anti-aging3 products
liquid hand soap3 products
blush2 products
baby wipes2 products
hair styling aide2 products
eye liner2 products
makeup primer2 products
makeup remover2 products
hair treatment/serum2 products
beach & sport sunscreen2 products
baby toothpaste2 products
baby soap1 products
tooth whitening1 products
baby shampoo1 products
baby sunscreen1 products
cuticle treatment1 products
eye shadow1 products
styling gel/lotion1 products
beard oil1 products

Contamination concerns

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Chemical
BENZETHONIUM CHLORIDE
METHYLPARABEN
TRICLOSAN

Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsFinal report 12/2016 available from CIR

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Allergies/immunotoxicity

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Concern Reference
Limited evidence of [[system]] toxicity or allergiesEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
Safe for use when formulated to be non-sensitizingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Data gaps

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Concern Reference
111 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • IFRA 1/2020
  • Final report 12/2016 available from CIR
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
  • Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

† About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer

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