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CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| bath oil/salts/soak | 30 products |
| toners/astringents | 24 products |
| lip gloss | 23 products |
| toothpaste | 21 products |
| antiperspirant/deodorant | 16 products |
| mask | 16 products |
| body wash/cleanser | 13 products |
| lipstick | 11 products |
| facial moisturizer/treatment | 10 products |
| facial cleanser | 8 products |
| exfoliant/scrub | 8 products |
| antiperspirant/deodorant (men's) | 7 products |
| moisturizer | 6 products |
| mouthwash | 6 products |
| baby wipes | 5 products |
| mascara | 5 products |
| shampoo | 5 products |
| conditioner | 5 products |
| liquid hand soap | 5 products |
| around-eye cream | 4 products |
| hand cream | 3 products |
| fragrance for women | 3 products |
| hair styling aide | 3 products |
| serums & essences | 3 products |
| hair treatment/serum | 3 products |
| makeup remover | 2 products |
| eye liner | 2 products |
| makeup primer | 2 products |
| beard oil | 2 products |
| after shave | 2 products |
| anti-aging | 2 products |
| beach & sport sunscreen | 2 products |
| baby toothpaste | 2 products |
| baby soap | 1 products |
| tooth whitening | 1 products |
| blush | 1 products |
| baby shampoo | 1 products |
| baby sunscreen | 1 products |
| cuticle treatment | 1 products |
| beard care | 1 products |
| styling gel/lotion | 1 products |
| concealer | 1 products |
| moisturizer with SPF | 1 products |
| body oil | 1 products |
Contamination concerns
| Chemical |
|---|
| BENZETHONIUM CHLORIDE |
| METHYLPARABEN |
| TRICLOSAN |
Use restrictions
| Concern | Reference |
|---|---|
| Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn) | IFRA 1/2020 |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Final report 12/2016 available from CIR |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Limited evidence of [[system]] toxicity or allergies | European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5 |
| Safe for use when formulated to be non-sensitizing | Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54; |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Safe for use when formulated to be non-irritating | Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54; |
Data gaps
| Concern | Reference |
|---|---|
| 111 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Data Sources
- IFRA 1/2020
- Final report 12/2016 available from CIR
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
- Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
