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CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (low), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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bath oil/salts/soak30 products
lip gloss29 products
toners/astringents26 products
antiperspirant/deodorant23 products
toothpaste21 products
mask20 products
body wash/cleanser14 products
facial moisturizer/treatment12 products
lipstick12 products
facial cleanser11 products
exfoliant/scrub9 products
moisturizer8 products
antiperspirant/deodorant (men's)7 products
mouthwash7 products
liquid hand soap6 products
baby wipes5 products
conditioner5 products
shampoo5 products
mascara5 products
around-eye cream4 products
body firming lotion4 products
serums & essences4 products
hair treatment/serum3 products
hair styling aide3 products
fragrance for women3 products
eye liner2 products
makeup primer2 products
recreational sunscreen2 products
anti-aging2 products
baby toothpaste2 products
setting powder/spray2 products
after shave2 products
makeup remover2 products
beard oil2 products
hand cream2 products
baby sunscreen1 products
daily use with SPF1 products
body oil1 products
cuticle treatment1 products
beard care1 products
baby shampoo1 products
baby soap1 products
styling gel/lotion1 products
concealer1 products
tooth whitening1 products

Contamination concerns

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Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsFinal report 12/2016 available from CIR

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Allergies/immunotoxicity

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Concern Reference
Limited evidence of [[system]] toxicity or allergiesEuropean Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
Safe for use when formulated to be non-sensitizingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Irritation (skin, eyes, or lungs)

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Concern Reference
Safe for use when formulated to be non-irritatingCosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;

Data gaps

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Concern Reference
111 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • IFRA 1/2020
  • Final report 12/2016 available from CIR
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Grapefruit, ext.; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; -; citrus paradisi macf; Essential oil of Grapefruit obtained from the peel of Citrus paradisi M., Rutaceae by expression and/or distilla; cas_numbers: 8016-20-4, 90045-43-5
  • Cosmetic Ingredient Review (CIR) 2017. CIR Assessments. Appears as: ; Chemical_Name: Citrus Grandis (Grapefruit) Seed Extract; ; ; Classification: QQQ02,QQQ53,QQQ54;
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

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