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CHLORHEXIDINE DIGLUCONATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate) and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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concealer65 products
hair color and bleaching16 products
moisturizer with SPF5 products
facial cleanser5 products
facial moisturizer/treatment4 products
blush4 products
around-eye cream3 products
CC cream3 products
serums & essences3 products
bronzer/highlighter2 products
conditioner2 products
moisturizer1 products
hair treatment/serum1 products
other eye makeup1 products
makeup remover1 products

Allergies/immunotoxicity

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Concern Reference
Human immune and respiratory toxicant or allergen - strong evidenceAssociation of Occupational and Environmental Clinics
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
Human any toxicant or allergen - strong evidenceAOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsJACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note)

Irritation (skin, eyes, or lungs)

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Concern Reference
Limited evidence of skin irritationNational Library of Medicine HazMap

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productJACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note)
2581 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
  • EWG Assessment of Open Scientific Literature
  • AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • JACT 12(3):201-23, 1993 IJT 18(2):69, 1999 (Note)
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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