Other ConcernsUse restrictions (moderate), Neurotoxicity (low), Endocrine disruption (low), and Non-reproductive organ system toxicity (moderate)
Unacceptable: EWG VERIFIED products cannot contain this ingredient
Cetylpyridinium Chloride is a quaternary ammonium salt.
See how this product scores for common concerns.
HIGHAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|Known human any toxicant or allergen||Open scientific literature|
|Possible human any toxicant or allergen||Open scientific literature|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)||Japan's Standards for Cosmetics|
Organ system toxicity (non-reproductive)
|Possible human any toxicant||Open scientific literature|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|One or more animal studies show any effects at moderate doses||Open scientific literature|
|One or more in vitro tests on mammalian cells demonstrate neurotoxicity||Open scientific literature|
|Prohibited for use in food||Open scientific literature|
|Associated with endocrine disruption||Open scientific literature|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|934 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
Multiple, additive exposure sources
|Designated as safe for general or specific, limited use in food||FDA Food Additive Status|
- Open scientific/peer reviewed literature
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.