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CAFFEINE
Score:
Data: Good
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Persistence and bioaccumulation (moderate)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| around-eye cream | 124 products |
| facial moisturizer/treatment | 72 products |
| mask | 67 products |
| concealer | 66 products |
| shampoo | 51 products |
| serums & essences | 50 products |
| daily use with SPF | 45 products |
| conditioner | 38 products |
| body firming lotion | 21 products |
| moisturizer | 19 products |
| makeup primer | 18 products |
| foundation | 18 products |
| facial cleanser | 17 products |
| recreational sunscreen | 16 products |
| hair treatment/serum | 16 products |
| antiperspirant/deodorant | 15 products |
| exfoliant/scrub | 14 products |
| body wash/cleanser | 13 products |
| BB cream | 13 products |
| hair styling aide | 11 products |
| lip liner | 10 products |
| lip plumper | 9 products |
| anti-aging | 9 products |
| 8 products | |
| sunless tanning | 8 products |
| hair-loss treatment | 7 products |
| lip gloss | 6 products |
| setting powder/spray | 6 products |
| shaving cream | 4 products |
| after shave | 4 products |
| bronzer/highlighter | 4 products |
| lipstick | 4 products |
| toners/astringents | 4 products |
| oil controller | 3 products |
| facial powder | 2 products |
| beard care | 2 products |
| styling gel/lotion | 2 products |
| lip balm | 2 products |
| hair spray | 2 products |
| tanning oil | 2 products |
| skin fading/lightener | 2 products |
| shaving cream (men's) | 2 products |
| muscle/joint soreness | 2 products |
| after sun product | 2 products |
| bar soap | 2 products |
| depilatory | 1 products |
| hand cream | 1 products |
| blush | 1 products |
| eye liner | 1 products |
| beard cleanser | 1 products |
| foot moisturizer | 1 products |
| body oil | 1 products |
| CC cream | 1 products |
| eye shadow | 1 products |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Persistent, bioaccumulative in wildlife | Emerging PBTs from peer-reviewed literature |
| Not suspected to be persistent | Environment Canada Domestic Substance List |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| 27683 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Cancer
| Concern | Reference |
|---|---|
| Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Data Sources
- Emerging PBTs from peer-reviewed literature
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
