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CAFFEINE

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Persistence and bioaccumulation (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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moisturizer with SPF64 products
serums & essences46 products
facial moisturizer/treatment38 products
around-eye cream35 products
concealer24 products
mask19 products
beach & sport sunscreen16 products
BB cream11 products
moisturizer10 products
shampoo9 products
facial cleanser9 products
antiperspirant/deodorant8 products
body firming lotion6 products
conditioner6 products
sunless tanning6 products
foundation6 products
makeup primer5 products
anti-aging4 products
toners/astringents4 products
body wash/cleanser3 products
oil controller3 products
hair treatment/serum3 products
exfoliant/scrub3 products
after shave3 products
bronzer/highlighter2 products
Facial Sun Care2 products
after sun product2 products
eye shadow2 products
CC cream2 products
body spray1 products
hair styling aide1 products
shaving cream1 products
hand cream1 products
hair spray1 products
shaving cream (men's)1 products
other eye makeup1 products
fragrance for men1 products

Persistence and bioaccumulation

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Concern Reference
Persistent, bioaccumulative in wildlifeEmerging PBTs from peer-reviewed literature
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Cancer

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Concern Reference
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 51;1991

Data gaps

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Concern Reference
27683 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data Sources

  • Emerging PBTs from peer-reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 51;1991
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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