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Data: Fair

Butoxyethanol

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (moderate), Non-reproductive organ system toxicity (low), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high)

SYNONYMS

2-BUTOXY- ETHANOL, 2-BUTOXYETHANOL, BUTOXYETHANOL, BUTYL GLYCOL, ETHANOL, 2-BUTOXY-, ETHANOL, 2BUTOXY, ETHYLENE GLYCOL MONOBUTYL ETHER, GLYCOL MONOBUTYL ETHER, and MONOBUTYL ETHYLENE GLYCOL ETHER

Butoxyethanol is an ether alcohol.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • MODERATE
    Developmental and Reingredientive Toxicity
  • MODERATE
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Classified as irritantCPS&Q - Classification & Labelling
Human any irritant - strong evidenceCosmetic Ingredient Review Assessments

Occupational hazards

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CONCERN REFERENCE
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Use restrictions

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CONCERN REFERENCE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Cancer

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CONCERN REFERENCE
Limited evidence of carcinogenicityEPA Integrated Risk Information System (IRIS)
Limited evidence of carcinogenicityAmer Conf of Gov't Industrial Hygienists - Carcinogens
Not likely to be carcinogenic in humansOpen scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens

Developmental/reproductive toxicity

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CONCERN REFERENCE
Limited evidence of reproductive toxicityNational Library of Medicine HazMap

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as toxic or harmfulCPS&Q - Classification & Labelling
Limited evidence of gastrointestinal or liver toxicityNational Library of Medicine HazMap
Limited evidence of respiratory toxicityScorecard.org Toxicity Information
One or more animal studies show any effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Categorized List of Inert Pesticide Ingredients
Classified as a low human health priorityEnvironment Canada Domestic Substance List
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
311 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Neurotoxicity

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CONCERN REFERENCE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
  • ACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
  • Open scientific/peer reviewed literature
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • EPA (U.S. Environmental Protection Agency). 1987 & 2005. Office of Pesticide Programs. Inert (other) Pesticide Ingredients in Pesticide Products - Categorized List of Inert (other) Pesticide Ingredients.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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