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BENZYL SALICYLATE
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Endocrine disruption (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| fragrance for women | 72 products |
| shampoo | 50 products |
| conditioner | 45 products |
| foundation | 43 products |
| moisturizer | 30 products |
| body wash/cleanser | 28 products |
| hair treatment/serum | 28 products |
| moisturizer with SPF | 24 products |
| facial moisturizer/treatment | 24 products |
| fragrance for men | 20 products |
| concealer | 20 products |
| lipstick | 19 products |
| hair styling aide | 16 products |
| hair spray | 16 products |
| serums & essences | 15 products |
| styling gel/lotion | 14 products |
| facial cleanser | 13 products |
| bronzer/highlighter | 12 products |
| hand cream | 12 products |
| liquid hand soap | 12 products |
| body spray | 11 products |
| antiperspirant/deodorant | 10 products |
| hair color and bleaching | 9 products |
| blush | 9 products |
| bar soap | 8 products |
| lip liner | 8 products |
| mask | 7 products |
| body firming lotion | 7 products |
| lip balm | 7 products |
| bath oil/salts/soak | 6 products |
| exfoliant/scrub | 6 products |
| sunless tanning | 6 products |
| antiperspirant/deodorant (men's) | 5 products |
| body oil | 5 products |
| facial powder | 4 products |
| detangler | 4 products |
| CC cream | 4 products |
| styling mousse/foam | 3 products |
| lip gloss | 3 products |
| toners/astringents | 3 products |
| baby lotion | 3 products |
| after shave | 2 products |
| diaper cream | 2 products |
| makeup primer | 2 products |
| beach & sport sunscreen | 2 products |
| foot moisturizer | 2 products |
| nail treatment | 2 products |
| makeup remover | 1 products |
| shaving cream | 1 products |
| polish remover | 1 products |
| lip plumper | 1 products |
| hair relaxer | 1 products |
| bubble bath | 1 products |
| cuticle treatment | 1 products |
| around-eye cream | 1 products |
| BB cream | 1 products |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Known human immune system toxicant or allergen | SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999. |
| Human [[system]] toxicant or allergen - strong evidence | Environmental Protection Agency (EPA) 2018. Safer Chemical Ingredients List (2018-02-28). Appears as: CAS: 118-58-1; List Name: Benzyl salicylate; TSCA Chemical Name: Benzoic acid, 2-hydroxy-, phenylmethyl ester |
| Limited evidence of [[system]] toxicity or allergies | European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Benzyl salicylate; benzyl 2-hydroxybenzoate; -; 2-hydroxybenzoic acid phenylmethyl ester; Benzoic acid, 2-hydroxy-, phenylmethyl ester; benzyl 2-hydroxybenzoaat; Benzyl 2-hydroxybenzoate; Benzyl 2-hydroxybenzoateBenzyl salicylate; BENZYL SALICILATE; B; cas_numbers: 118-58-1 |
Endocrine disruption
| Concern | Reference |
|---|---|
| Benzyl salicylate demonstrated estrogenic activity by increasing the proliferation of breast cancer cells in vitro. | Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5): 422-34. |
Ecotoxicology
| Concern | Reference |
|---|---|
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| 49 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Use restrictions
| Concern | Reference |
|---|---|
| Restricted in cosmetics - labeling requirement for allergens | CosIng |
Data Sources
- SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
- Environmental Protection Agency (EPA) 2018. Safer Chemical Ingredients List (2018-02-28). Appears as: CAS: 118-58-1; List Name: Benzyl salicylate; TSCA Chemical Name: Benzoic acid, 2-hydroxy-, phenylmethyl ester
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Benzyl salicylate; benzyl 2-hydroxybenzoate; -; 2-hydroxybenzoic acid phenylmethyl ester; Benzoic acid, 2-hydroxy-, phenylmethyl ester; benzyl 2-hydroxybenzoaat; Benzyl 2-hydroxybenzoate; Benzyl 2-hydroxybenzoateBenzyl salicylate; BENZYL SALICILATE; B; cas_numbers: 118-58-1
- Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5): 422-34.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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