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BENZYL BENZOATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Endocrine disruption (low), Ecotoxicology (low), and Occupational hazards (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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lipstick128 products
lip gloss114 products
fragrance for women99 products
moisturizer66 products
conditioner64 products
hair treatment/serum54 products
shampoo53 products
hair styling aide49 products
foundation41 products
facial moisturizer/treatment39 products
mask36 products
lip balm33 products
fragrance for men32 products
serums & essences30 products
hair spray28 products
body wash/cleanser26 products
facial cleanser20 products
bronzer/highlighter18 products
body firming lotion17 products
eye shadow17 products
hair color and bleaching15 products
exfoliant/scrub15 products
lip plumper14 products
hand cream14 products
blush13 products
liquid hand soap13 products
styling gel/lotion12 products
antiperspirant/deodorant12 products
concealer12 products
body oil11 products
body spray8 products
styling mousse/foam8 products
sunless tanning8 products
daily use with SPF8 products
antiperspirant/deodorant (men's)7 products
makeup primer7 products
bath oil/salts/soak7 products
detangler5 products
recreational sunscreen5 products
bar soap4 products
anti-aging4 products
lip balm with SPF4 products
foot moisturizer4 products
shaving cream4 products
toners/astringents4 products
brow liner4 products
baby lotion3 products
polish remover3 products
makeup remover3 products
BB cream3 products
diaper cream2 products
after shave2 products
cuticle treatment2 products
around-eye cream2 products
nail treatment2 products
after sun product2 products
bubble bath2 products
foot cleansing2 products
hair relaxer2 products
2 products
beard oil2 products
setting powder/spray2 products
shaving cream (men's)1 products
muscle/joint soreness1 products
body powder1 products
facial powder1 products
oil controller1 products
baby shampoo1 products
vapor rubs1 products
eye makeup remover1 products
baby sunscreen1 products
hand sanitizer1 products

Allergies/immunotoxicity

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Concern Reference
Known human any toxicant or allergenOpinion on Frangrance allergens in cosmetics (2011), EU Cosmetics Directive
Possible human immune system toxicant or allergenSCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Restricted in cosmetics - labeling requirement for allergensCosIng

Ecotoxicology

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Concern Reference
Wildlife and environmental toxicityCPS&Q - Classification & Labelling
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Endocrine disruption

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Concern Reference
Benzyl benzoate demonstrated estrogenic activity by increasing the proliferation of breast cancer cells in vitro.Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5):422-34.

Data gaps

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Concern Reference
467 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 36(Suppl 3):5-30, 2017

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Opinion on Frangrance allergens in cosmetics (2011), EU Cosmetics Directive
  • SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • IFRA 1/2020
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5):422-34.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • IJT 36(Suppl 3):5-30, 2017

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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