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BENZYL BENZOATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Endocrine disruption (low), Ecotoxicology (low), and Occupational hazards (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is HIGH

Products with this Ingredient

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lipstick108 products
lip gloss104 products
fragrance for women86 products
moisturizer45 products
foundation32 products
conditioner26 products
shampoo26 products
body wash/cleanser24 products
fragrance for men24 products
mask23 products
serums & essences22 products
facial moisturizer/treatment21 products
hair styling aide17 products
hair treatment/serum17 products
eye shadow15 products
lip balm15 products
bronzer/highlighter14 products
blush13 products
concealer12 products
hair spray11 products
facial cleanser10 products
hand cream9 products
hair color and bleaching9 products
exfoliant/scrub8 products
bath oil/salts/soak7 products
styling gel/lotion6 products
makeup primer6 products
body spray5 products
lip plumper5 products
body firming lotion5 products
body oil5 products
sunless tanning5 products
antiperspirant/deodorant5 products
brow liner4 products
styling mousse/foam4 products
bar soap4 products
toners/astringents4 products
beach & sport sunscreen3 products
liquid hand soap3 products
antiperspirant/deodorant (men's)3 products
lip balm with SPF2 products
nail treatment2 products
beard oil2 products
detangler2 products
moisturizer with SPF2 products
hair relaxer2 products
makeup remover2 products
cuticle treatment2 products
shaving cream2 products
hand sanitizer1 products
vapor rubs1 products
anti-aging1 products
oil controller1 products
foot moisturizer1 products
diaper cream1 products
polish remover1 products
after shave1 products
facial powder1 products
after sun product1 products
baby shampoo1 products

Allergies/immunotoxicity

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Concern Reference
Known human any toxicant or allergenOpinion on Frangrance allergens in cosmetics (2011), EU Cosmetics Directive
Possible human immune system toxicant or allergenSCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Use restrictions

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Concern Reference
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA 1/2020
Restricted in cosmetics - labeling requirement for allergensCosIng

Ecotoxicology

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Concern Reference
Wildlife and environmental toxicityCPS&Q - Classification & Labelling
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Endocrine disruption

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Concern Reference
Benzyl benzoate demonstrated estrogenic activity by increasing the proliferation of breast cancer cells in vitro.Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5):422-34.

Data gaps

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Concern Reference
467 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 36(Suppl 3):5-30, 2017

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Opinion on Frangrance allergens in cosmetics (2011), EU Cosmetics Directive
  • SCCPNFP, 1999 "Opinion Concerning Fragrance Allergy In Consumers," Scientific Committee On Cosmetic Products And Non-Food Products. SCCNFP/0017/98 Final, December 1999.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • IFRA 1/2020
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Charles AK, Darbre PD 2009. Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro. J Appl Toxicol. 29(5):422-34.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • IJT 36(Suppl 3):5-30, 2017

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer