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Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Non-reproductive organ system toxicity (moderate), and Occupational hazards (high)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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lipstick154 products
beach & sport sunscreen93 products
foundation83 products
shampoo76 products
conditioner69 products
moisturizer65 products
body wash/cleanser58 products
facial moisturizer/treatment56 products
fragrance for women50 products
lip gloss44 products
moisturizer with SPF43 products
liquid hand soap35 products
serums & essences34 products
facial cleanser26 products
eye shadow25 products
exfoliant/scrub21 products
bronzer/highlighter21 products
mascara19 products
fragrance for men14 products
mask14 products
hair color and bleaching13 products
makeup remover13 products
hair treatment/serum13 products
shaving cream13 products
hand cream12 products
styling gel/lotion11 products
around-eye cream11 products
facial powder11 products
lip balm with SPF9 products
baby sunscreen9 products
makeup primer9 products
lip liner8 products
antiperspirant/deodorant8 products
body firming lotion6 products
hair spray6 products
bubble bath6 products
blush5 products
sunless tanning5 products
brow liner5 products
bath oil/salts/soak4 products
toners/astringents4 products
body oil4 products
CC cream4 products
concealer4 products
eye liner4 products
shaving cream (men's)3 products
foot moisturizer3 products
lip balm3 products
baby shampoo3 products
after sun product3 products
detangler2 products
baby lotion2 products
baby soap2 products
hair styling aide2 products
anti-aging1 products
body spray1 products
baby bubble bath1 products
baby wipes1 products
bar soap1 products
skin fading/lightener1 products
makeup with SPF1 products
toothpaste1 products
eye makeup remover1 products
after shave1 products
oil controller1 products
baby toothpaste1 products
vapor rubs1 products

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Fragrance subject to restrictions: safe only within recommended use or concentration limitsn)IFRA_Standard_135html

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as toxic or harmfulCPS&Q - Classification & Labelling


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Concern Reference
One or more human case studies show possible allergenic or allergenic effectsVerecken, 1998
Associated with immunotoxicity or allergiesNational Library of Medicine HazMap

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 20(S3):23-50, 2001 reopened 06/10
5667 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 20(S3):23-50, 2001 reopened 06/10

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at .
  • IFRA_Standard_135html
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Verecken, 1998
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • IJT 20(S3):23-50, 2001 reopened 06/10
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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