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Data: Limited

Benzethonium Chloride

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (moderate)

SYNONYMS

BENZENEMETHANAMINIUM, N,N-DIMETHYL-N-[2-[2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY]ETHYL]-, CHLORIDE; BENZYLDIMETHYL[2-[2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY]ETHYL]AMMONIUM CHLORIDE, BENZENEMETHANAMINIUM, N,NDIMETHYLN[2[2[4(1,1,3,3TETRAMETHYLBUTYL)PHENOXY]ETHOXY]ETHYL], CHLORIDE, BENZETHONIUM CHLORIDE, BENZETHONIUM CHLORIDE SOLUTION, BENZYL(DIMETHYL)(2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY)-ETHYL)AMMONIUM CHLORIDE, DIIS OBUTYL PHENOXY ETHOXY ETHYL DIMETHYL BENZYL AMMONIUM CHLORIDE, N,N-DIMETHYL-N-[2-[2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY]ETHYL]-, BENZENEMETHANAMINIUM, and N,N-DIMETHYL-N-[2-[2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY]ETHYL]BENZENEMETHANAMINIUM

Benzethonium Chloride is a quaternary ammonium salt. In the United States, Benzethonium Chloride may be used as an active ingredient in OTC drug products. When used as an active drug ingredient, the established name is Benzethonium Chloride.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • HIGH
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • MODERATE
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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liquid hand soap10 products
foot odor control10 products
body wash/cleanser4 products
body powder4 products
baby wipes2 products
hand sanitizer2 products
serums & essences1 products
body spray1 products
bar soap1 products
facial moisturizer/treatment1 products
cuticle treatment1 products
antiperspirant/deodorant1 products
shaving cream1 products

Allergies/immunotoxicity

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CONCERN REFERENCE
Known human any toxicant or allergenOpen scientific literature

Use restrictions

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CONCERN REFERENCE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Developmental/reproductive toxicity

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CONCERN REFERENCE
One or more animal studies show any effects at moderate dosesOpen scientific literature

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
400 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
  • Open scientific/peer reviewed literature
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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