Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|liquid hand soap||88 products|
|hand sanitizer||44 products|
|bar soap||25 products|
|facial cleanser||13 products|
|body wash/cleanser||11 products|
|makeup remover||9 products|
|eye makeup remover||9 products|
|hair styling aide||6 products|
|daily use with SPF||5 products|
|hair treatment/serum||5 products|
|baby lotion||4 products|
|hand cream||4 products|
|body firming lotion||3 products|
|facial moisturizer/treatment||3 products|
|sunless tanning||2 products|
|styling gel/lotion||2 products|
|baby wipes||2 products|
|brow liner||2 products|
|shaving cream||1 products|
|BB cream||1 products|
|damaged skin treatment||1 products|
|lip balm||1 products|
|around-eye cream||1 products|
|hair spray||1 products|
|A similar compound is a known human toxicant or allergen||AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.|
|Human immune and respiratory toxicant or allergen - strong evidence||Association of Occupational and Environmental Clinics|
|Human skin toxicant or allergen - strong evidence||JACT 8(4):589-625, 1989 confirmed 06/06|
|Limited evidence of immune system toxicity or allergies||National Library of Medicine HazMap|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)||Japan's Standards for Cosmetics|
|Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications||JACT 8(4):589-625, 1989 confirmed 06/06|
|A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals.||Vanessa E Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||JACT 8(4):589-625, 1989 confirmed 06/06|
|2541 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|Classified as a low human health priority||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
- AOEC (Association of Occupational and Environmental Clinics) 2012. Asthmagen compilation - AEOC exposures codes.
- AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
- JACT 8(4):589-625, 1989 confirmed 06/06
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- Vanessa E Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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