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ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Enhanced skin absorption, Use restrictions (low), Neurotoxicity (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| foundation | 32 products |
| conditioner | 25 products |
| facial moisturizer/treatment | 23 products |
| shampoo | 21 products |
| facial cleanser | 14 products |
| moisturizer | 13 products |
| serums & essences | 11 products |
| moisturizer with SPF | 9 products |
| body wash/cleanser | 8 products |
| exfoliant/scrub | 7 products |
| hand cream | 7 products |
| mask | 7 products |
| hair styling aide | 7 products |
| body firming lotion | 7 products |
| BB cream | 6 products |
| makeup remover | 6 products |
| concealer | 5 products |
| hair spray | 5 products |
| baby lotion | 5 products |
| eye liner | 3 products |
| body oil | 3 products |
| styling gel/lotion | 3 products |
| around-eye cream | 2 products |
| bubble bath | 2 products |
| toners/astringents | 2 products |
| makeup primer | 2 products |
| other eye makeup | 2 products |
| anti-aging | 2 products |
| mascara | 2 products |
| detangler | 2 products |
| hair treatment/serum | 2 products |
| baby soap | 1 products |
| diaper cream | 1 products |
| bronzer/highlighter | 1 products |
| baby oil | 1 products |
| beach & sport sunscreen | 1 products |
| facial powder | 1 products |
| muscle/joint soreness | 1 products |
| hair color and bleaching | 1 products |
| foot moisturizer | 1 products |
| styling mousse/foam | 1 products |
| liquid hand soap | 1 products |
| skin fading/lightener | 1 products |
| bath oil/salts/soak | 1 products |
| bar soap | 1 products |
| baby toothpaste | 1 products |
Enhanced skin absorption
| Concern | Reference |
|---|---|
| Penetration enhancer | IJT 18(S3):33-40, 1999 |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Weak evidence of possible pregnancy/birth effects associated with chamomile consumption. | Laura Cuzzolin, Francesco Francini-Pesenti, Giovanna Verlato, Marco Joppi, Paola Baldelli & Giuseppina Benoni 2010. Use of herbal products among 392 Italian pregnant women: focus on pregnancy outcome. Pharmacoepidemiology and drug safety 19(11), 1151-8. |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Safe for use when formulated to be non-sensitizing | Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3040; Chemical_Name: Anthemis nobilis flower extract; ; ; Classification: QQQ02, QQQ54; |
| May cause an allergic skin reaction. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Causes skin irritation | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| May be fatal if swallowed and enters airways | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Use restrictions
| Concern | Reference |
|---|---|
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 36(Suppl 1):57-66, 2017 |
Neurotoxicity
| Concern | Reference |
|---|---|
| Derivatives of this species demonstrate neuromuscular effects in animals. | Zsolt Sándor, Loránd Barthó, Róbert Papp, DezsÅ‘ Kelemen, Attila Horváth, TÃmea Bencsik, Judit Hohmann, Katalin Veres, Javad Mottaghipisheh & DezsÅ‘ Csupor 2018. Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles. Frontiers in pharmacology 9, 323 |
Ecotoxicology
| Concern | Reference |
|---|---|
| toxic to aquatic life with long lasting effects | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | IJT 18(S3):33-40, 1999 |
| 43 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | IJT 18(S3):33-40, 1999 |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
Data Sources
- IJT 18(S3):33-40, 1999
- Laura Cuzzolin, Francesco Francini-Pesenti, Giovanna Verlato, Marco Joppi, Paola Baldelli & Giuseppina Benoni 2010. Use of herbal products among 392 Italian pregnant women: focus on pregnancy outcome. Pharmacoepidemiology and drug safety 19(11), 1151-8.
- Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3040; Chemical_Name: Anthemis nobilis flower extract; ; ; Classification: QQQ02, QQQ54;
- European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- IJT 36(Suppl 1):57-66, 2017
- Zsolt Sándor, Loránd Barthó, Róbert Papp, DezsÅ‘ Kelemen, Attila Horváth, TÃmea Bencsik, Judit Hohmann, Katalin Veres, Javad Mottaghipisheh & DezsÅ‘ Csupor 2018. Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles. Frontiers in pharmacology 9, 323
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
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