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ANTHEMIS NOBILIS (CHAMOMILE) FLOWER EXTRACT
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Enhanced skin absorption, Use restrictions (low), Neurotoxicity (low), Non-reproductive organ system toxicity (low), and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| conditioner | 26 products |
| facial moisturizer/treatment | 24 products |
| shampoo | 20 products |
| moisturizer | 13 products |
| facial cleanser | 11 products |
| foundation | 11 products |
| serums & essences | 10 products |
| moisturizer with SPF | 9 products |
| body wash/cleanser | 8 products |
| hand cream | 7 products |
| mask | 6 products |
| exfoliant/scrub | 6 products |
| makeup remover | 6 products |
| BB cream | 6 products |
| hair styling aide | 6 products |
| body firming lotion | 6 products |
| hair spray | 5 products |
| baby lotion | 4 products |
| anti-aging | 4 products |
| concealer | 4 products |
| around-eye cream | 3 products |
| eye liner | 3 products |
| body oil | 3 products |
| other eye makeup | 2 products |
| mascara | 2 products |
| styling gel/lotion | 2 products |
| toners/astringents | 2 products |
| bubble bath | 2 products |
| detangler | 2 products |
| bronzer/highlighter | 1 products |
| beach & sport sunscreen | 1 products |
| baby oil | 1 products |
| diaper cream | 1 products |
| foot moisturizer | 1 products |
| liquid hand soap | 1 products |
| skin fading/lightener | 1 products |
| makeup primer | 1 products |
| baby toothpaste | 1 products |
| baby soap | 1 products |
| toothpaste | 1 products |
| after sun product | 1 products |
Enhanced skin absorption
| Concern | Reference |
|---|---|
| Penetration enhancer | IJT 18(S3):33-40, 1999 |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Weak evidence of possible pregnancy/birth effects associated with chamomile consumption. | Laura Cuzzolin, Francesco Francini-Pesenti, Giovanna Verlato, Marco Joppi, Paola Baldelli & Giuseppina Benoni 2010. Use of herbal products among 392 Italian pregnant women: focus on pregnancy outcome. Pharmacoepidemiology and drug safety 19(11), 1151-8. |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Safe for use when formulated to be non-sensitizing | Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3040; Chemical_Name: Anthemis nobilis flower extract; ; ; Classification: QQQ02, QQQ54; |
| May cause an allergic skin reaction. | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Causes skin irritation | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| May be fatal if swallowed and enters airways | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Use restrictions
| Concern | Reference |
|---|---|
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 36(Suppl 1):57-66, 2017 |
Neurotoxicity
| Concern | Reference |
|---|---|
| Derivatives of this species demonstrate neuromuscular effects in animals. | Zsolt Sándor, Loránd Barthó, Róbert Papp, DezsÅ‘ Kelemen, Attila Horváth, TÃmea Bencsik, Judit Hohmann, Katalin Veres, Javad Mottaghipisheh & DezsÅ‘ Csupor 2018. Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles. Frontiers in pharmacology 9, 323 |
Ecotoxicology
| Concern | Reference |
|---|---|
| toxic to aquatic life with long lasting effects | European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7 |
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | IJT 18(S3):33-40, 1999 |
| 43 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | IJT 18(S3):33-40, 1999 |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
Data Sources
- IJT 18(S3):33-40, 1999
- Laura Cuzzolin, Francesco Francini-Pesenti, Giovanna Verlato, Marco Joppi, Paola Baldelli & Giuseppina Benoni 2010. Use of herbal products among 392 Italian pregnant women: focus on pregnancy outcome. Pharmacoepidemiology and drug safety 19(11), 1151-8.
- Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3040; Chemical_Name: Anthemis nobilis flower extract; ; ; Classification: QQQ02, QQQ54;
- European Chemicals Agency (ECHA) 2020. GHS Data from ECHA Website. Appears as: chemical_names: ANTHEMIS NOBILIS (CHAMOMILE) FLOWER OIL; cas_numbers: 8015-92-7
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- IJT 36(Suppl 1):57-66, 2017
- Zsolt Sándor, Loránd Barthó, Róbert Papp, DezsÅ‘ Kelemen, Attila Horváth, TÃmea Bencsik, Judit Hohmann, Katalin Veres, Javad Mottaghipisheh & DezsÅ‘ Csupor 2018. Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles. Frontiers in pharmacology 9, 323
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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