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ALUMINUM CHLOROHYDRATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Non-reproductive organ system toxicity (moderate), and Ecotoxicology (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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antiperspirant/deodorant18 products
antiperspirant/deodorant (men's)7 products
toners/astringents1 products
body spray1 products
facial powder1 products

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients
Use is restricted in Canadian cosmetics.Health Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Limited evidence of any toxicityKlaassen, C, M. Amdur and J. Doull (eds.). Casarett and Doull

Cancer

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Concern Reference
This study found a relationship between use of antiperspirant product use, breast cancer risk, and aluminum concentration in breast tissue in women.Caroline Linhart, Nicole Concin, Michael Hubalek, Daniel Egle, Susanne Taucher, Herbert H Lindner, Christopher Exley, Evi M. Morandi, Heribert Talasz & Hanno Ulmer. 2017. Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer: A Case-Control Study. EBioMedicine 21, 79-85.
This study found that treating mouse mammary cells with aluminum chloride, at concentrations observed in human breast tissue, formed large metastatic tumors when implanted back into mice.Stefano J Mandriota, Mirna Tenan, Paolo Ferrari & André-Pascal Sappino. 2016. Aluminium chloride promotes tumorigenesis and metastasis in normal murine mammary gland epithelial cells. International journal of cancer 139(12), 2781-2790.
This small (n = 54) epidemiological study found no link between breast cancer and antiperspirant use in women.Dana K Mirick, Scott Davis & David B. Thomas. 2002. Antiperspirant use and the risk of breast cancer. Journal of the National Cancer Institute 94(20), 1578-80.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
200 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • Health Canada 2011. List of Prohibited and Restricted Cosmetic Ingredients. Canada
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Klaassen, C, M. Amdur and J. Doull (eds.). Casarett and Doull
  • Caroline Linhart, Nicole Concin, Michael Hubalek, Daniel Egle, Susanne Taucher, Herbert H Lindner, Christopher Exley, Evi M. Morandi, Heribert Talasz & Hanno Ulmer. 2017. Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer: A Case-Control Study. EBioMedicine 21, 79-85.
  • Stefano J Mandriota, Mirna Tenan, Paolo Ferrari & André-Pascal Sappino. 2016. Aluminium chloride promotes tumorigenesis and metastasis in normal murine mammary gland epithelial cells. International journal of cancer 139(12), 2781-2790.
  • Dana K Mirick, Scott Davis & David B. Thomas. 2002. Antiperspirant use and the risk of breast cancer. Journal of the National Cancer Institute 94(20), 1578-80.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer