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ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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lipstick372 products
conditioner125 products
recreational sunscreen104 products
lip gloss97 products
mask92 products
lip balm88 products
concealer86 products
foundation80 products
moisturizer78 products
facial moisturizer/treatment76 products
shampoo71 products
body wash/cleanser69 products
facial cleanser68 products
hand sanitizer50 products
daily use with SPF45 products
bronzer/highlighter43 products
eye shadow42 products
baby wipes39 products
makeup remover37 products
lip balm with SPF37 products
serums & essences37 products
blush35 products
antiperspirant/deodorant35 products
hair treatment/serum33 products
liquid hand soap31 products
bar soap31 products
mascara30 products
toners/astringents29 products
hair styling aide26 products
body firming lotion25 products
makeup primer22 products
hand cream21 products
CC cream20 products
exfoliant/scrub19 products
baby sunscreen19 products
BB cream19 products
hair color and bleaching18 products
lip plumper17 products
after sun product15 products
eye liner15 products
lip liner14 products
hair spray13 products
body spray13 products
baby oil13 products
styling gel/lotion12 products
baby powder12 products
body oil12 products
setting powder/spray12 products
eye makeup remover11 products
around-eye cream11 products
antiperspirant/deodorant (men's)11 products
beard care11 products
baby shampoo10 products
tanning oil10 products
bath oil/salts/soak9 products
anti-aging9 products
fragrance for women8 products
facial powder7 products
detangler7 products
baby lotion6 products
bubble bath6 products
brow liner6 products
shaving cream (men's)6 products
shaving cream6 products
glitter6 products
styling mousse/foam5 products
toothpaste5 products
5 products
pore strips5 products
foot moisturizer4 products
sunless tanning4 products
baby soap3 products
diaper cream3 products
foot cleansing3 products
nail treatment2 products
depilatory2 products
foot odor control2 products
hair relaxer2 products
cuticle treatment2 products
body powder2 products
beard oil2 products
eyelash glue2 products
muscle/joint soreness1 products
after shave1 products
vapor rubs1 products
baby bubble bath1 products
damaged skin treatment1 products
fragrance for men1 products
hair-loss treatment1 products

Cancer

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Concern Reference
Possible human carcinogenIARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
Cancer - strong evidenceNTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
Limited or incomplete evidence of cancer according to safety/hazard data – scientific review cannot classify as human carcinogen due to data gapsNTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894

Developmental/reproductive toxicity

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Concern Reference
3 month rat study produced significant sperm damageCIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 26(S2):1-50, 2007

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 26(S2):1-50, 2007
Missing safety data noted by cosmetic industry reviewIJT 26(S2):1-50, 2007
151 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitIJT 26(S2):1-50, 2007

Data Sources

  • IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
  • NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
  • NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894
  • CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.
  • IJT 26(S2):1-50, 2007
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if a product likely contains the non-decolorized whole leaf aloe vera, which is known to cause cancer. The score will be lower if the decolorized version of the ingredient is used.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer