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ALOE BARBADENSIS (ALOE VERA) LEAF EXTRACT
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| lipstick | 301 products |
| conditioner | 118 products |
| recreational sunscreen | 99 products |
| foundation | 75 products |
| lip gloss | 74 products |
| facial moisturizer/treatment | 68 products |
| moisturizer | 65 products |
| mask | 62 products |
| lip balm | 58 products |
| body wash/cleanser | 57 products |
| shampoo | 55 products |
| concealer | 52 products |
| facial cleanser | 49 products |
| eye shadow | 45 products |
| daily use with SPF | 43 products |
| serums & essences | 43 products |
| baby wipes | 41 products |
| bronzer/highlighter | 36 products |
| lip balm with SPF | 35 products |
| makeup remover | 34 products |
| blush | 34 products |
| hair treatment/serum | 28 products |
| toners/astringents | 24 products |
| mascara | 24 products |
| antiperspirant/deodorant | 24 products |
| bar soap | 23 products |
| body firming lotion | 20 products |
| hand cream | 19 products |
| baby sunscreen | 18 products |
| exfoliant/scrub | 17 products |
| hair color and bleaching | 17 products |
| hair styling aide | 17 products |
| hand sanitizer | 15 products |
| BB cream | 15 products |
| lip liner | 14 products |
| eye liner | 14 products |
| around-eye cream | 13 products |
| liquid hand soap | 13 products |
| makeup primer | 13 products |
| lip plumper | 13 products |
| CC cream | 12 products |
| after sun product | 11 products |
| setting powder/spray | 11 products |
| hair spray | 10 products |
| styling gel/lotion | 9 products |
| baby shampoo | 9 products |
| body oil | 9 products |
| tanning oil | 9 products |
| baby oil | 9 products |
| eye makeup remover | 8 products |
| baby powder | 8 products |
| antiperspirant/deodorant (men's) | 8 products |
| body spray | 7 products |
| beard care | 7 products |
| anti-aging | 6 products |
| bubble bath | 6 products |
| facial powder | 6 products |
| detangler | 6 products |
| baby lotion | 5 products |
| styling mousse/foam | 5 products |
| shaving cream | 5 products |
| diaper cream | 4 products |
| shaving cream (men's) | 4 products |
| glitter | 4 products |
| foot moisturizer | 3 products |
| bath oil/salts/soak | 3 products |
| baby soap | 3 products |
| brow liner | 3 products |
| toothpaste | 3 products |
| mouthwash | 3 products |
| pore strips | 2 products |
| hair-loss treatment | 2 products |
| eyelash glue | 2 products |
| depilatory | 1 products |
| after shave | 1 products |
| foot odor control | 1 products |
| vapor rubs | 1 products |
| fragrance for women | 1 products |
| cuticle treatment | 1 products |
| baby bubble bath | 1 products |
| damaged skin treatment | 1 products |
| body powder | 1 products |
| fragrance for men | 1 products |
| 1 products | |
| beard oil | 1 products |
| foot cleansing | 1 products |
Cancer
| Concern | Reference |
|---|---|
| Possible human carcinogen | IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113. |
| Cancer - strong evidence | NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910. |
| Limited or incomplete evidence of cancer according to safety/hazard data – scientific review cannot classify as human carcinogen due to data gaps | NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894 |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| 3 month rat study produced significant sperm damage | CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review. |
Use restrictions
| Concern | Reference |
|---|---|
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 26(S2):1-50, 2007 |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | IJT 26(S2):1-50, 2007 |
| Missing safety data noted by cosmetic industry review | IJT 26(S2):1-50, 2007 |
| 151 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limit | IJT 26(S2):1-50, 2007 |
Data Sources
- IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
- NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
- NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894
- CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.
- IJT 26(S2):1-50, 2007
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- This ingredient’s score is higher if a product likely contains the non-decolorized whole leaf aloe vera, which is known to cause cancer. The score will be lower if the decolorized version of the ingredient is used.
- Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
