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ALOE BARBADENSIS (ALOE VERA) LEAF JUICE

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Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms

  • Use restrictions (low)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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moisturizer431 products
conditioner426 products
shampoo426 products
facial moisturizer/treatment354 products
body wash/cleanser306 products
mask275 products
recreational sunscreen271 products
liquid hand soap244 products
facial cleanser234 products
toners/astringents185 products
serums & essences181 products
hair treatment/serum155 products
hand sanitizer136 products
daily use with SPF134 products
body firming lotion127 products
antiperspirant/deodorant124 products
hair styling aide124 products
foundation118 products
shaving cream109 products
hand cream109 products
exfoliant/scrub101 products
after sun product87 products
around-eye cream66 products
makeup remover64 products
baby lotion56 products
styling gel/lotion55 products
bath oil/salts/soak53 products
baby sunscreen51 products
baby soap48 products
bubble bath48 products
baby shampoo48 products
baby wipes47 products
bar soap46 products
toothpaste45 products
hair color and bleaching36 products
mouthwash36 products
36 products
detangler33 products
makeup primer30 products
anti-aging29 products
shaving cream (men's)26 products
hair spray25 products
after shave24 products
baby bubble bath24 products
setting powder/spray24 products
foot moisturizer20 products
antiperspirant/deodorant (men's)18 products
mascara17 products
sunless tanning17 products
CC cream17 products
brow liner16 products
BB cream16 products
body spray14 products
muscle/joint soreness13 products
beard care13 products
lip balm11 products
styling mousse/foam11 products
bronzer/highlighter11 products
blush9 products
eye makeup remover8 products
fragrance for women8 products
facial powder8 products
beard cleanser8 products
concealer7 products
diaper cream6 products
eye liner6 products
body powder5 products
eye shadow5 products
oil controller5 products
lipstick5 products
lip balm with SPF5 products
foot odor control4 products
tooth whitening4 products
baby oil4 products
damaged skin treatment4 products
lip plumper4 products
depilatory3 products
body oil3 products
tanning oil3 products
foot cleansing3 products
polish remover2 products
baby toothpaste2 products
other eye makeup2 products
depilatory (men's)1 products
skin fading/lightener1 products
hair-loss treatment1 products
hair relaxer1 products
vapor rubs1 products
fragrance for men1 products

Cancer

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Concern Reference
Possible human carcinogenIARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
Cancer - strong evidenceNTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
Limited or incomplete evidence of cancer according to safety/hazard data – scientific review cannot classify as human carcinogen due to data gapsNTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894

Developmental/reproductive toxicity

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Concern Reference
3 month rat study produced significant sperm damageCIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 26(S2):1-50, 2007

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 26(S2):1-50, 2007
Missing safety data noted by cosmetic industry reviewIJT 26(S2):1-50, 2007
103 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitIJT 26(S2):1-50, 2007

Data Sources

  • IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
  • NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
  • NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894
  • CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.
  • IJT 26(S2):1-50, 2007
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

† About this Ingredient's Score Range

  • This ingredient’s score is higher if a product likely contains the non-decolorized whole leaf aloe vera, which is known to cause cancer. The score will be lower if the decolorized version of the ingredient is used.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer

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