Menu Close Menu

Menu

ALOE BARBADENSIS (ALOE VERA) LEAF JUICE

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

Expand content Collapse content
beach & sport sunscreen402 products
moisturizer227 products
shampoo222 products
conditioner217 products
facial moisturizer/treatment216 products
body wash/cleanser181 products
moisturizer with SPF151 products
mask137 products
facial cleanser128 products
liquid hand soap104 products
antiperspirant/deodorant71 products
foundation70 products
serums & essences69 products
toners/astringents62 products
exfoliant/scrub51 products
body firming lotion48 products
shaving cream47 products
toothpaste45 products
hand cream39 products
makeup remover39 products
baby lotion38 products
around-eye cream36 products
baby sunscreen36 products
hair styling aide35 products
hair treatment/serum33 products
hand sanitizer29 products
after sun product27 products
hair color and bleaching25 products
mouthwash24 products
bubble bath23 products
BB cream23 products
baby shampoo22 products
baby soap22 products
bar soap20 products
concealer19 products
anti-aging17 products
mascara17 products
shaving cream (men's)16 products
CC cream15 products
styling gel/lotion14 products
makeup primer13 products
baby bubble bath12 products
eye liner12 products
baby wipes11 products
brow liner11 products
detangler11 products
after shave11 products
sunless tanning10 products
lip balm9 products
antiperspirant/deodorant (men's)9 products
Facial Sun Care9 products
bath oil/salts/soak9 products
hair spray8 products
foot moisturizer7 products
body spray6 products
oil controller6 products
lip balm with SPF6 products
lipstick4 products
eye shadow4 products
blush4 products
eye makeup remover3 products
muscle/joint soreness3 products
tooth whitening3 products
other men's products3 products
Tanning Sprays3 products
beard care3 products
baby toothpaste3 products
other eye makeup2 products
diaper cream2 products
styling mousse/foam2 products
makeup with SPF2 products
skin fading/lightener1 products
body oil1 products
lip plumper1 products
facial powder1 products
nail treatment1 products
depilatory1 products
baby oil1 products
polish remover1 products
beard oil1 products
damaged skin treatment1 products
beard cleanser1 products

Cancer

Expand content Collapse content
Concern Reference
Possible human carcinogenIARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
Cancer - strong evidenceNTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
Limited or incomplete evidence of cancer according to safety/hazard data – scientific review cannot classify as human carcinogen due to data gapsNTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894

Developmental/reproductive toxicity

Expand content Collapse content
Concern Reference
3 month rat study produced significant sperm damageCIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.

Use restrictions

Expand content Collapse content
Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 26(S2):1-50, 2007

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 26(S2):1-50, 2007
Missing safety data noted by cosmetic industry reviewIJT 26(S2):1-50, 2007
103 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitIJT 26(S2):1-50, 2007

Data Sources

  • IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
  • NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
  • NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894
  • CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.
  • IJT 26(S2):1-50, 2007
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

About this Ingredient's Score Range

  • This ingredient’s score is higher if a product likely contains the non-decolorized whole leaf aloe vera, which is known to cause cancer. The score will be lower if the decolorized version of the ingredient is used.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer