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ALOE BARBADENSIS (ALOE VERA) GEL

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (low)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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beach & sport sunscreen208 products
moisturizer96 products
shampoo93 products
facial moisturizer/treatment92 products
conditioner87 products
moisturizer with SPF81 products
body wash/cleanser72 products
facial cleanser68 products
mask55 products
foundation54 products
liquid hand soap43 products
serums & essences43 products
exfoliant/scrub27 products
toners/astringents23 products
toothpaste21 products
antiperspirant/deodorant19 products
hand cream18 products
hair treatment/serum18 products
around-eye cream15 products
baby sunscreen15 products
shaving cream14 products
baby lotion14 products
hair styling aide14 products
makeup remover12 products
concealer10 products
BB cream10 products
after sun product10 products
mouthwash10 products
anti-aging9 products
CC cream8 products
baby bubble bath8 products
baby shampoo7 products
hair spray7 products
after shave7 products
baby soap7 products
sunless tanning6 products
hand sanitizer6 products
brow liner6 products
eye liner6 products
detangler5 products
bubble bath5 products
mascara5 products
styling gel/lotion4 products
shaving cream (men's)4 products
baby wipes4 products
oil controller4 products
body oil4 products
lipstick4 products
eye shadow4 products
blush4 products
makeup primer4 products
baby toothpaste3 products
body spray3 products
bar soap3 products
lip balm3 products
lip balm with SPF3 products
body firming lotion2 products
styling mousse/foam2 products
makeup with SPF2 products
nail treatment1 products
facial powder1 products
antiperspirant/deodorant (men's)1 products
tooth whitening1 products
beard oil1 products
hair color and bleaching1 products
muscle/joint soreness1 products
other eye makeup1 products

Cancer

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Concern Reference
Possible human carcinogenIARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
Cancer - strong evidenceNTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
Limited or incomplete evidence of cancer according to safety/hazard data – scientific review cannot classify as human carcinogen due to data gapsNTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894

Developmental/reproductive toxicity

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Concern Reference
One or more animal studies show any effects at moderate dosesCIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 26(S2):1-50, 2007

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productIJT 26(S2):1-50, 2007
Missing safety data noted by cosmetic industry reviewIJT 26(S2):1-50, 2007
374 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitIJT 26(S2):1-50, 2007

Data Sources

  • IARC (International Agency for Research on Cancer) 2016. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-113.
  • NTP (National Toxicology Program) 2013. NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF A NONDECOLORIZED WHOLE LEAF EXTRACT OF ALOE BARBADENSIS MILLER (ALOE VERA) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES). NIH Publication No. 13-5910.
  • NTP (National Toxicology Program) 2010. NTP TECHNICAL REPORT ON THE PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA in SKH-1 MICE. NIH Publication No. 10-5894
  • CIR (2006) 2006 CIR Compendium. Washington, Cosmetic Ingredient Review.
  • IJT 26(S2):1-50, 2007
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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