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ALCOHOL DENATURED

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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fragrance for women165 products
beach & sport sunscreen159 products
shampoo133 products
hair spray111 products
facial moisturizer/treatment103 products
mask85 products
foundation84 products
body spray81 products
fragrance for men80 products
serums & essences77 products
mascara73 products
eye liner53 products
hair color and bleaching49 products
moisturizer with SPF43 products
toners/astringents34 products
antiperspirant/deodorant33 products
conditioner28 products
brow liner28 products
lipstick28 products
hair styling aide28 products
makeup primer26 products
body wash/cleanser25 products
hair treatment/serum25 products
facial cleanser22 products
setting powder/spray22 products
baby sunscreen20 products
antiperspirant/deodorant (men's)19 products
bronzer/highlighter18 products
sunless tanning17 products
body firming lotion17 products
moisturizer16 products
hand sanitizer15 products
around-eye cream12 products
concealer11 products
styling gel/lotion10 products
nail polish10 products
exfoliant/scrub9 products
liquid hand soap9 products
lip gloss8 products
BB cream8 products
after sun product7 products
glitter7 products
6 products
after shave5 products
makeup remover5 products
styling mousse/foam5 products
facial powder5 products
oil controller4 products
anti-aging4 products
eye shadow4 products
CC cream4 products
tanning oil4 products
eyelash glue3 products
bath oil/salts/soak3 products
polish remover3 products
shaving cream3 products
nail treatment2 products
foot moisturizer2 products
depilatory2 products
other eye makeup2 products
beard care2 products
foot odor control1 products
hair-loss treatment1 products
shaving cream (men's)1 products
baby wipes1 products
toothpaste1 products
baby shampoo1 products
bar soap1 products
beard oil1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Data gaps

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Concern Reference
Insufficient data to determine safetyIJT 27 (S1):1-43, 2008
78649 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • IJT 27 (S1):1-43, 2008
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.

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