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ALCOHOL DENATURED

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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fragrance for women143 products
beach & sport sunscreen120 products
shampoo103 products
facial moisturizer/treatment91 products
serums & essences74 products
fragrance for men69 products
mascara66 products
body spray65 products
foundation65 products
hair spray61 products
mask58 products
eye liner52 products
hair color and bleaching46 products
moisturizer with SPF35 products
brow liner28 products
lipstick28 products
body wash/cleanser26 products
conditioner25 products
toners/astringents24 products
makeup primer22 products
facial cleanser18 products
bronzer/highlighter18 products
moisturizer15 products
hand sanitizer14 products
hair styling aide13 products
antiperspirant/deodorant12 products
sunless tanning12 products
antiperspirant/deodorant (men's)11 products
exfoliant/scrub11 products
around-eye cream11 products
hair treatment/serum11 products
concealer11 products
body firming lotion8 products
nail polish8 products
lip gloss8 products
BB cream8 products
liquid hand soap6 products
glitter6 products
5 products
styling gel/lotion5 products
after sun product5 products
facial powder4 products
CC cream4 products
oil controller3 products
eyelash glue3 products
makeup remover3 products
styling mousse/foam3 products
beard care3 products
after shave3 products
bath oil/salts/soak2 products
depilatory2 products
other eye makeup2 products
anti-aging2 products
shaving cream2 products
lip balm2 products
makeup with SPF1 products
nail treatment1 products
baby wipes1 products
baby sunscreen1 products
baby shampoo1 products
bar soap1 products
beard oil1 products
body oil1 products
hair-loss treatment1 products
foot moisturizer1 products
shaving cream (men's)1 products
polish remover1 products
toothpaste1 products
pore strips1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Data gaps

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Concern Reference
Insufficient data to determine safetyIJT 27 (S1):1-43, 2008
78649 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • IJT 27 (S1):1-43, 2008
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.

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