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ALCOHOL DENATURED

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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fragrance for women65 products
body spray32 products
facial moisturizer/treatment28 products
shampoo26 products
hair color and bleaching25 products
hair spray23 products
mask22 products
lipstick17 products
body wash/cleanser15 products
mascara13 products
eye liner12 products
serums & essences12 products
brow liner8 products
beach & sport sunscreen7 products
moisturizer6 products
toners/astringents6 products
facial cleanser6 products
fragrance for men6 products
makeup primer5 products
concealer5 products
antiperspirant/deodorant4 products
sunless tanning4 products
body firming lotion3 products
oil controller3 products
antiperspirant/deodorant (men's)3 products
foundation3 products
hair styling aide3 products
nail polish3 products
hand sanitizer3 products
bath oil/salts/soak2 products
around-eye cream2 products
exfoliant/scrub2 products
hair treatment/serum2 products
conditioner2 products
styling gel/lotion2 products
anti-aging2 products
after sun product1 products
makeup remover1 products
body oil1 products
beard oil1 products
liquid hand soap1 products
shaving cream (men's)1 products
pore strips1 products
baby wipes1 products
after shave1 products
foot moisturizer1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerMutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Data gaps

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Concern Reference
Insufficient data to determine safetyIJT 27 (S1):1-43, 2008
78649 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • IJT 27 (S1):1-43, 2008
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.

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