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ALCOHOL DENATURED

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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fragrance for women204 products
recreational sunscreen160 products
shampoo145 products
hair spray127 products
fragrance for men109 products
facial moisturizer/treatment107 products
foundation99 products
body spray94 products
mask91 products
mascara80 products
serums & essences78 products
eye liner54 products
hair color and bleaching53 products
daily use with SPF44 products
toners/astringents38 products
antiperspirant/deodorant37 products
conditioner31 products
hair styling aide30 products
lipstick28 products
makeup primer27 products
setting powder/spray27 products
hair treatment/serum27 products
body wash/cleanser26 products
hand sanitizer26 products
facial cleanser25 products
brow liner25 products
nail polish25 products
antiperspirant/deodorant (men's)24 products
sunless tanning19 products
body firming lotion19 products
bronzer/highlighter19 products
moisturizer18 products
baby sunscreen18 products
around-eye cream13 products
styling gel/lotion12 products
exfoliant/scrub11 products
concealer11 products
after sun product11 products
liquid hand soap10 products
BB cream9 products
glitter9 products
lip gloss8 products
after shave7 products
7 products
styling mousse/foam6 products
bath oil/salts/soak6 products
makeup remover5 products
facial powder5 products
oil controller4 products
eye shadow4 products
CC cream4 products
tanning oil4 products
eyelash glue3 products
anti-aging3 products
polish remover3 products
shaving cream3 products
beard care3 products
nail treatment2 products
foot moisturizer2 products
depilatory2 products
other eye makeup2 products
foot odor control1 products
shaving cream (men's)1 products
baby wipes1 products
hair relaxer1 products
toothpaste1 products
baby shampoo1 products
bar soap1 products
beard oil1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Data gaps

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Concern Reference
Insufficient data to determine safetyIJT 27 (S1):1-43, 2008
78649 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • IJT 27 (S1):1-43, 2008
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.

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