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ALCOHOL DENATURED

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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fragrance for women131 products
beach & sport sunscreen120 products
mask100 products
shampoo83 products
facial moisturizer/treatment69 products
foundation65 products
lipstick65 products
serums & essences63 products
fragrance for men56 products
hair spray53 products
body spray51 products
mascara41 products
hair color and bleaching36 products
moisturizer with SPF34 products
body wash/cleanser27 products
brow liner25 products
eye liner24 products
conditioner23 products
eye shadow21 products
facial cleanser19 products
toners/astringents15 products
bronzer/highlighter14 products
antiperspirant/deodorant12 products
makeup primer12 products
moisturizer11 products
hair styling aide10 products
sunless tanning8 products
exfoliant/scrub8 products
body firming lotion8 products
BB cream8 products
hair treatment/serum8 products
around-eye cream7 products
hand sanitizer6 products
lip liner6 products
antiperspirant/deodorant (men's)6 products
liquid hand soap6 products
concealer5 products
styling gel/lotion4 products
nail polish4 products
facial powder4 products
CC cream4 products
oil controller3 products
after sun product3 products
anti-aging2 products
bath oil/salts/soak2 products
makeup remover2 products
shaving cream2 products
after shave1 products
foot moisturizer1 products
makeup with SPF1 products
shaving cream (men's)1 products
body oil1 products
baby sunscreen1 products
baby wipes1 products
beard oil1 products
nail treatment1 products
toothpaste1 products
other eye makeup1 products
baby shampoo1 products
polish remover1 products
depilatory1 products
pore strips1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Multiple, additive exposure sources

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Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Data gaps

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Concern Reference
Insufficient data to determine safetyIJT 27 (S1):1-43, 2008
78649 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • IJT 27 (S1):1-43, 2008
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.

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