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ALCOHOL DENATURED
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), and Multiple, additive exposure sources (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| fragrance for women | 65 products |
| body spray | 32 products |
| facial moisturizer/treatment | 28 products |
| shampoo | 26 products |
| hair color and bleaching | 25 products |
| hair spray | 23 products |
| mask | 22 products |
| lipstick | 17 products |
| body wash/cleanser | 15 products |
| mascara | 13 products |
| eye liner | 12 products |
| serums & essences | 12 products |
| brow liner | 8 products |
| beach & sport sunscreen | 7 products |
| moisturizer | 6 products |
| toners/astringents | 6 products |
| facial cleanser | 6 products |
| fragrance for men | 6 products |
| makeup primer | 5 products |
| concealer | 5 products |
| antiperspirant/deodorant | 4 products |
| sunless tanning | 4 products |
| body firming lotion | 3 products |
| oil controller | 3 products |
| antiperspirant/deodorant (men's) | 3 products |
| foundation | 3 products |
| hair styling aide | 3 products |
| nail polish | 3 products |
| hand sanitizer | 3 products |
| bath oil/salts/soak | 2 products |
| around-eye cream | 2 products |
| exfoliant/scrub | 2 products |
| hair treatment/serum | 2 products |
| conditioner | 2 products |
| styling gel/lotion | 2 products |
| anti-aging | 2 products |
| after sun product | 1 products |
| makeup remover | 1 products |
| body oil | 1 products |
| beard oil | 1 products |
| liquid hand soap | 1 products |
| shaving cream (men's) | 1 products |
| pore strips | 1 products |
| baby wipes | 1 products |
| after shave | 1 products |
| foot moisturizer | 1 products |
Enhanced skin absorption
| Concern | Reference |
|---|---|
| Penetration enhancer | Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5. |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
| Classified as medium human health priority | Environment Canada Domestic Substance List |
| Limited evidence of sense organ toxicity | Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria). |
Data gaps
| Concern | Reference |
|---|---|
| Insufficient data to determine safety | IJT 27 (S1):1-43, 2008 |
| 78649 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Miscellaneous
| Concern | Reference |
|---|---|
| Occupational hazards related to handling | CPS&Q - Classification & Labelling |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
- IJT 27 (S1):1-43, 2008
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
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