Find products and ingredients Learn how Skin Deep® works Meet our experts Discover EWG VERIFIED™

Data: Robust

Acrylamide

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

Other Concerns

Use restrictions (high), Non-reproductive organ system toxicity (high), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high)

SYNONYMS

2PROPENAMIDE and ACRYLAMIDE

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • MODERATE
    Developmental and Reingredientive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

Expand content Collapse content
facial moisturizer/treatment1 products
styling gel/lotion1 products

Organ system toxicity (non-reproductive)

Expand content Collapse content
CONCERN REFERENCE
Known human respiratory toxicantEPA Hazardous Air Pollutants
Classified as a high human health priorityEnvironment Canada Domestic Substance List
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as toxic or harmfulCPS&Q - Classification & Labelling
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Irritation (skin, eyes, or lungs)

Expand content Collapse content
CONCERN REFERENCE
Classified as irritantCPS&Q - Classification & Labelling

Use restrictions

Expand content Collapse content
CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsCanada - Prohibited and Restricted Cosmetics Ingredients

Occupational hazards

Expand content Collapse content
CONCERN REFERENCE
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Developmental/reproductive toxicity

Expand content Collapse content
CONCERN REFERENCE
Possible human developmental toxicantCalifornia EPA Proposition 65
Limited evidence of developmental toxicityCPS&Q - Classification & Labelling
Limited evidence of reproductive toxicityNational Library of Medicine HazMap
Limited evidence of reproductive toxicityScorecard.org Toxicity Information

Cancer

Expand content Collapse content
CONCERN REFERENCE
Possible human carcinogenInt'l Agency for Research on Cancer (IARC) - Carcinogens
Possible human carcinogenNTP Report on Carcinogens, 11th Edition
Possible human carcinogenEPA Integrated Risk Information System (IRIS)
Possible human carcinogenCalifornia EPA Proposition 65
Possible human carcinogenCPS&Q - Classification & Labelling
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens
Limited evidence of carcinogenicityAmer Conf of Gov't Industrial Hygienists - Carcinogens
Possible mutagenCPS&Q - Classification & Labelling
Cancer - limited evidenceSilent Spring's Mammary Carcinogens Reviews Database

Allergies/immunotoxicity

Expand content Collapse content
CONCERN REFERENCE
Limited evidence of immune system toxicity or allergiesCPS&Q - Classification & Labelling
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Ecotoxicology

Expand content Collapse content
CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Expand content Collapse content
CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Neurotoxicity

Expand content Collapse content
CONCERN REFERENCE
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Data gaps

Expand content Collapse content
CONCERN REFERENCE
9099 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
  • California EPA (California Environmental Protection Agency). 9/2008. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986. Chemicals known to the State to cause cancer or reproductive toxicity.
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NTP (National Toxicology Program). 2005. Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program.
  • EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
  • NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html.
  • ACGIH (American Conference of Governmental Industrial Hygienists) 2008. ACGIH cancer classification system. www.acgih.org.
  • Rudel RA, KR Attfield, JN Schifano and JG Brody. Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. CANCER Supplement. 2007 Jun 15;109(12):2635-2666.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

Can’t find your product?

Enter the ingredients in EWG’s Build Your Own Report tool to get an approximate score for that product.

BUILD YOUR OWN REPORT

EWG research
on the go

Find personal care, cleaning, and food products on the EWG Healthy Living app.

DOWNLOAD THE APP