EWG Skin Deep® | What is 8-HYDROXYQUINOLINE SULFATE

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED®

Data: Fair

8 Hydroxyquinoline Sulfate

This ingredient’s score is higher if used in products that will not be immediately rinsed off due to increased risk of absorption.
This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high), Non-reproductive organ system toxicity (low), and Occupational hazards (high)

SYNONYMS

● 8-HYDROXYQUINOLINE SULFATE

● 8-QUINOLINOL, SULFATE (2:1)(SALT)

● 8QUINOLINOL, SULFATE (2:1) (SALT)

● CHINOSOL

● HYDROXY-8-QUINOLINIUM SULFATE

● OXINE SULFATE

● OXYQUINOLINE SULFATE

● SULFATE (2:1)(SALT) 8-QUINOLINOL

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation

Oxyquinoline Sulfate is a salt of oxyquinoline and sulfuric acid.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

hair color and bleaching	3 products
muscle/joint soreness	1 products

Occupational hazards

CONCERN	REFERENCE
Allowed workplace exposures restricted to low doses	CPS&Q - Classification & Labelling

Use restrictions

CONCERN	REFERENCE
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any	CosIng
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics	Canada - Prohibited and Restricted Cosmetics Ingredients
Recommended restricted in cosmetics - use, concentration, or manufacturing restrictions - Product type restrictions or differences noted in safety assessment by industry panel	Cosmetic Ingredient Review Assessments
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications	Cosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as toxic or harmful	CPS&Q - Classification & Labelling
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Miscellaneous

CONCERN	REFERENCE
Prohibited for use in food	FDA Food Additive Status

Data gaps

CONCERN	REFERENCE
Safety unknown for products left on skin	Cosmetic Ingredient Review Assessments
6428 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Persistence and bioaccumulation

CONCERN	REFERENCE
Not suspected to be persistent	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED^® mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability