Other Concerns
Neurotoxicity (moderate), Endocrine disruption (low), Multiple, additive exposure sources (moderate), and Ecotoxicology (low)SYNONYMS
Unacceptable
Unacceptable: EWG VERIFIED products cannot contain this ingredient
Common concerns
See how this product scores for common concerns.
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LOWCancer
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LOWAllergies & Immunotoxicity
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MODERATEDevelopmental and Reproductive Toxicity
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LOWUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
nail polish | 92 products |
nail treatment | 10 products |
brow liner | 2 products |
1 products | |
nail glue | 1 products |
eye shadow | 1 products |
Developmental/reproductive toxicity
CONCERN | REFERENCE |
---|---|
Possible human reproductive toxicant | Open scientific literature |
One or more animal studies show developmental cardiotoxicity effects at low doses | Open scientific literature |
Multiple, additive exposure sources
CONCERN | REFERENCE |
---|---|
In other consumer products besides personal care products | Open scientific literature |
Neurotoxicity
CONCERN | REFERENCE |
---|---|
One or more animal studies show neurodevelopmental effects at very low doses | Open scientific literature |
Endocrine disruption
CONCERN | REFERENCE |
---|---|
One or more studies show endocrine disruption at low doses | Open scientific literature |
One or more animal studies show endocrine disruption at moderate doses | Open scientific literature |
Human case studies indicate endocrine disruption effect | Open scientific literature |
Associated with endocrine disruption | Open scientific literature |
Allergies/immunotoxicity
CONCERN | REFERENCE |
---|---|
Limited evidence of any toxicity or allergies | Open scientific literature |
Limited evidence of immune system toxicity or allergies | National Library of Medicine HazMap |
Ecotoxicology
CONCERN | REFERENCE |
---|---|
Wildlife and environmental toxicity | Open scientific literature |
Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Informational
CONCERN | REFERENCE |
---|---|
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Open scientific literature |
Persistence and bioaccumulation
CONCERN | REFERENCE |
---|---|
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Not suspected to be persistent | Environment Canada Domestic Substance List |
Data gaps
CONCERN | REFERENCE |
---|---|
3015 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Organ system toxicity (non-reproductive)
CONCERN | REFERENCE |
---|---|
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
- Open scientific/peer reviewed literature
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.