chemical information
CAS RN:
00591-78-6
Chemical Class:
Semivolatile organic compounds
Chemical SubClass
Found in these people:
Andrea Martin, Bill Moyers, Davis Baltz, Lucy Waletsky, Michael Lerner, Sharyle Patton, Lexi Rome, Monique Harden, Charlotte Brody
Found in these locations:
Sausalito, CA; NJ, USA; Berkeley, CA; Pleasantville, NY; Bolinas, CA; Mill Valley, CA; New Orleans, LA; Round Hill, VA
Summary
Laboratory animals. The primary target of 2-hexanone is the nervous system. Specific effects include loss of coordination, axon swelling, nerve demyelination, nerve degeneration, abnormal pupil response to light, and decreased motor conduction velocity. Behavioral neurotoxicity, such as decreased exploratory and avoidance conditioning behavior, results from fetal exposure. Higher doses of 2-hexanone cause fetal death, low birth weight, testicular toxicity and possible alterations of liver and immune function (ATSDR 1992).
Humans. In 1973, it was reported that workers exposed to 2-hexanone for 10 months during the production of plastic-coated and color-printed fabrics lost weight and developed nerve disease. The workers developed muscle weakness, loss of reflexes, slower nerve conduction velocities and reduced alibility discriminate pain, touch, temperature, or vibration in hands and feet (ATSDR 1992).
2-Hexanone
Industrial solvent; in humans, damages nervous system; in animals, fetal and adult exposure causes significant neurotoxicity.
2-Hexanone has been found in 9 of the 9 people tested in EWG/Commonweal studies.
Results for 2-Hexanone
Showing results from EWG/Commonweal Study #1, industrial chemicals and pesticides in adults
EWG/Commonweal results
- found in 9 of 9 people in the group
