chemical information


Chemical Class:

Brominated dioxin

Chemical SubClass

Pentabrominated dioxin

Found in these people:

Cord Blood Sample 15, Cord Blood Sample 13

Found in these locations:

not found


Brominated dioxins and furans are toxic, persistent, bioaccumulative and lipophilic ('fat-loving'). They build up in human tissues, are stored in fatty tissues and fluid, such as breast milk, and can be passed on to fetuses and infants during pregnancy and lactation. Brominated dioxins and furans are formed unintentionally, either from incineration of wastes that include consumer products infused with brominated flame retardants like PBDEs, or as trace contaminants in mixtures of bromine-containing chemicals. Brominated dioxins and furans have dioxin-like activity, meaning that they cause birth defects in animals and otherwise disrupt the reproductive development, immune and hormone systems. They add to the total dioxin body burden, which are near levels where effects may be occurring in the general population (Birnbaum 2003; EPA 2000a; WHO 1998).

1,2,3,7,8-PeBDD (pentadioxin)

1,2,3,7,8-PeBDD (pentadioxin) has been found in 2 of the 23 people tested in EWG/Commonweal studies.

Top health concerns for 1,2,3,7,8-PeBDD (pentadioxin) (References)

health concern or target organ weight of evidence
Immune system (including sensitization and allergies)limited

Results for 1,2,3,7,8-PeBDD (pentadioxin)

in blood serum (lipid weight)

Showing results from EWG/Commonweal Study #4, industrial chemicals and pesticides in cord blood, Pollution in Minority Newborns, EWG Study #3, industrial chemicals and pesticides in adults

EWG/Commonweal results

  • geometric mean: 1.36 pg/g (lipid weight) in blood serum
  • found in 2 of 23 people in the group
pg/g (lipid weight) in blood serum 41.8

1,2,3,7,8-PeBDD (pentadioxin) results

Detailed toxicity classifications (References)

classification governing entity/references
Limited evidence in humans - immune system toxicityBirnbaum, L. S., D. F. Staskal, et al. (2003). Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ Int 29(6): 855-60.