developmentb
C

HEXYL SALICYLATE

 

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation.

Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Low Concern
 
Developmental &
Reproductive Toxicity
 
Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of developmental/endocrine/reproductive effects; damage to vision; skin irritation/allergies/damage
HEXYL SALICYLATE can be found in 39 products.
Print
 

Evidence

Health issue
 
Level of Concern
 
Source
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
Causes skin irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
The Cosmetic Ingredient Review Panel concluded this substance is safe for use when formulated to be non-sensitizing.
 
some
 
Cosmetic Ingredient Review (CIR): CIR Assessments
The Cosmetic Ingredient Review panel concludes this substance is safe for use when formulated to be non-irritating.
 
some
 
Cosmetic Ingredient Review (CIR): CIR Assessments
Hexyl salicylate caused skin irritation in animals.
 
some
 
Nada Oršolić, Jadranka Skurić, Domagoj Dikić & Gabrijela Stanić. 2014. Inhibitory effect of a propolis on di-n-propyl disulfide or n-hexyl salycilate-induced skin irritation, oxidative stress and inflammatory responses in mice. Fitoterapia 93, 18-30.
Skin sensitization observed in animal testing.
 
some
 
A. Lapczynski, L. Jones, D. McGinty, S. Bhatia, C. S. Letizia & A. M. Api. 2007. Fragrance material review on hexyl salicylate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 45 Suppl 1, S410-7.
Equivocal evidence of minor skin irritation in human and animal studies.
 
low
 
A. Lapczynski, L. Jones, D. McGinty, S. Bhatia, C. S. Letizia & A. M. Api. 2007. Fragrance material review on hexyl salicylate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 45 Suppl 1, S410-7.
No evidence of skin sensitization in limited human testing.
 
low
 
Niels H. Bennike, Claus Zachariae & Jeanne D. Johansen. 2019. Optimal patch test concentration for three widely used sensitizing fragrance substances without mandatory labelling in cosmetics. Contact dermatitis 80(5), 325-327.
The European Commission's Scientific Committee on Consumer Safety reports this substance shows negative results for causing contact allergy in humans.
 
low
 
EU Cosmetics Directive: Opinion on Frangrance allergens in cosmetics (2011)
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
Privacy Policy | Legal Disclaimer | Methodology | FAQs