EWG's Guide to Healthy Cleaning | BETULA PUBESCENS (WHITE BIRCH) BARK EXTRACT

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HOME / INGREDIENTS / Betula pubescens (white birch) bark extract

BETULA PUBESCENS (WHITE BIRCH) BARK EXTRACT

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COMMONLY FOUND IN

cleaner, all-purpose/multi-surface cleaner, counter surface

SYNONYMS

WHITE BIRCH BARK EXTRACT, EXTRACT OF BIRCH BARK, EXTRACT OF BETULA ALBA BARK, BIRCH, BETULA ALBA, EXT., BIRCH (BETULA ALBA) BARK EXTRACT, BIRCH BARK EXTRACT, EXT. BIRCH, BETULA ALBA, BETULA ALBA EXT. BIRCH, BETULA PUBESCENS BARK EXTRACT, BETULA PUBESCENS (WHITE BIRCH) BARK EXTRACT

Common Concerns

See how this product scores for common concerns.

No Data

Asthma / Respiratory
SOME

Skin Allergies & Irritation
No Data

Developmental & Reproductive Toxicity
LOW

Cancer
No Data

Environment

Top Scoring Factors

No information available on this substance.

Ingredient concerns

CONCERNS

Health Issue	Level of Concern	Source

A peer-reviewed article reports that birch bark extract impacted immune cell function in vitro.	some	Jona Freysdottir, Marino Boas Sigurpalsson, Sesselja Omarsdottir, Elin S. Olafsdottir, Arnor Vikingsson & Ingibjorg Hardardottir. 2011. Ethanol extract from birch bark (Betula pubescens) suppresses human dendritic cell mediated Th1 responses and directs it towards a Th17 regulatory response in vitro. Immunology letters 136(1), 90-6.
A peer-reviewed study reports this substance has antioxidant properties.	some	Wendan Zhang, Honghong Jiang, Jianxi Yang, Miaomiao Jin, Yingfeng Du, Qian Sun, Liang Cao & Huijun Xu. 2019. Safety assessment and antioxidant evaluation of betulin by LC-MS combined with free radical assays. Analytical biochemistry 587, 113460.
A human case study reports contact dermatitis caused by this substance.	some	Ulf Meyer-Hoffert & Jochen Brasch. 2013. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact dermatitis 68(6), 382-3.
A peer-reviewed article concludes this substance has low propensity to impact liver enzyme function based on in vitro tests.	low	Madhav Seervi, Shweta Lotankar, Shrikant Barbar & Sadhana Sathaye. 2016. Assessment of cytochrome P450 inhibition and induction potential of lupeol and betulin in rat liver microsomes. Drug metabolism and personalized therapy 31(2), 115-22.
This substance was not mutagenic or genotoxic in an in vitro test.	low	T. S. Frolova, T. P. Kukina & O. I. Sinitsyna. 1900. [Genotoxic and Mutagenic Properties of Synthetic Betulinic and Betulonic Acids]. Bioorganicheskaia khimiia 41(4), 462-7.
A review article reports that betulin has anticancer properties.	low	Sylwia Katarzyna Król, Michał Kiełbus, Adolfo Rivero-Müller & Andrzej Stepulak. 2015. Comprehensive review on betulin as a potent anticancer agent. BioMed research international 2015, 584189.