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TRICLOSAN

 
Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Some Concern
 
Developmental &
Reproductive Toxicity
 
Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of chronic aquatic toxicity; acute aquatic toxicity; general ecotoxicity
TRICLOSAN can be found in 15 products.
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Evidence

Health issue
 
Level of Concern
 
Source
Very toxic to aquatic life
 
high
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Very toxic to aquatic life with long lasting effects
 
high
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
European Union Ecolabel program data shows this substance has high chronic toxicity to aquatic life
 
some
 
Detergents Ingredients Database - EU Ecolabel
European Union Ecolabel program data shows this substance has very high acute toxicity to aquatic life
 
some
 
Detergents Ingredients Database - EU Ecolabel
This review article reports triclosan can act as an endocrine disruptor
 
some
 
Andrea B. Dann & Alice Hontela. 2011. Triclosan: environmental exposure, toxicity and mechanisms of action. Journal of applied toxicology : JAT 31(4), 285-311.
risk of promoting bacterial resistance
 
some
 
Gilles Bedoux, Benoit Roig, Olivier Thomas, Virginie Dupont & Barbara Le Bot. 2012. Occurrence and toxicity of antimicrobial triclosan and by-products in the environment. Environmental science and pollution research international 19(4), 1044-65.
risk of developing antimicrobial-resistant bacteria
 
some
 
Allison E. Aiello, Elaine L. Larson & Stuart B. Levy. 2007. Consumer antibacterial soaps: effective or just risky?. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 45 Suppl 2, S137-47.
alters endocrine function in a variety of species
 
some
 
Leah M. Zorrilla, Emily K. Gibson, Susan C. Jeffay, Kevin M. Crofton, Woodrow R. Setzer, Ralph L. Cooper & Tammy E. Stoker. 2009. The effects of triclosan on puberty and thyroid hormones in male Wistar rats. Toxicological sciences : an official journal of the Society of Toxicology 107(1), 56-64.
alters endocrine function in a variety of species
 
some
 
Leah M. Zorrilla, Emily K. Gibson, Susan C. Jeffay, Kevin M. Crofton, Woodrow R. Setzer, Ralph L. Cooper & Tammy E. Stoker. 2009. The effects of triclosan on puberty and thyroid hormones in male Wistar rats. Toxicological sciences : an official journal of the Society of Toxicology 107(1), 56-64.
decreases thyroid hormone levels
 
some
 
Katie B. Paul, Joan M. Hedge, Ruby Bansal, R. Thomas Zoeller, Robert Peter, Michael J. Devito & Kevin M. Crofton. 2012. Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: Dynamic and kinetic evaluation of a putative mode-of-action. Toxicology.
decreases thyroid hormone levels
 
some
 
Katie B. Paul, Joan M. Hedge, Michael J. Devito & Kevin M. Crofton. 2010. Short-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in Young Long-Evans rats. Toxicological sciences : an official journal of the Society of Toxicology 113(2), 367-79.
Triclosan may negatively affect immune function in people
 
some
 
Erin M. Rees Clayton, Megan Todd, Jennifer Beam Dowd & Allison E. Aiello. 2011. The impact of bisphenol A and triclosan on immune parameters in the U.S. population, NHANES 2003-2006. Environmental health perspectives 119(3), 390-6.
A peer-reviewed study reports that triclosan impairs cardiac and skeletal muscle function.
 
some
 
Gennady Cherednichenko, Nipavan Chiamvimonvat, Kurt G. Beam, Bruce D. Hammock, Nils H. Schebb, Genaro C. Barrientos, Wei Feng, Erika B. Fritsch, Ning Li, Valeriy Timofeyev, Roger A. Bannister, Rui Zhang & Isaac N. Pessah. 2012. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proceedings of the National Academy of Sciences of the United States of America 109(35), 14158-63.
Causes skin irritation
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
NTP Toxcast scored 2.5-3.5
 
some
 
EWG Toxcast Analysis - National Toxicology Program (NTP)
triclosan affected estrogen-mediated responses and suppressed thyroid hormone
 
some
 
Tammy E. Stoker, Emily K. Gibson & Leah M. Zorrilla. 2010. Triclosan exposure modulates estrogen-dependent responses in the female wistar rat. Toxicological sciences : an official journal of the Society of Toxicology 117(1), 45-53.
Causes serious eye irritation
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
The European Union Ecolabel program reports this substance in inherently biodegradable.
 
low
 
Detergents Ingredients Database - EU Ecolabel
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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