Health issue
Level of Concern
Source
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
high
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
high
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
high
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
moderate
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
some
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
some
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
The CIR panel reports equivocal evidence that tocopherol may act as a tumor promoter.
some
Cosmetic Ingredient Review (CIR): CIR Assessments
May cause an allergic skin reaction
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
The CIR panel reports that tocopherol was a dermal sensitizer in an animal study and contact allergy has been reported in human tests and case studies, although occurrence is rare.
some
Cosmetic Ingredient Review (CIR): CIR Assessments
Tocopherol functions as an antioxidant in personal care products.
low
Cosmetic Ingredient Review (CIR): CIR Assessments
Tocopherol was not genotoxic in in vitro tests with mammalian cells.
low
Cosmetic Ingredient Review (CIR): CIR Assessments
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
low
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
low
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
low
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
Health issue
Level of Concern
Source
Impurity: HYDROQUINONE
Suspected of causing genetic defects
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Suspected of causing cancer
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Very toxic to aquatic life
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
eye damage
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: HYDROQUINONE
Harmful if swallowed
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
confirmed animal carcinogen with unknown relevance to humans
some
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: HYDROQUINONE
May cause an allergic skin reaction
Only in: Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
some
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
NTP Toxcast scored 1.5-2.5
some
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: HYDROQUINONE
Not classifiable as to its carcinogenicity to humans
low
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: HYDROQUINONE
eye irritation
low
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis