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TOCOPHEROL

 

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation.

Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Low Concern
 
Developmental &
Reproductive Toxicity
 
No Data, Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of blood-related effects; developmental/endocrine/reproductive effects; damage to vision
TOCOPHEROL can be found in 28 products.
Print
 

Evidence

Health issue
 
Level of Concern
 
Source
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
 
high
 
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
 
high
 
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
 
high
 
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
 
moderate
 
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
 
some
 
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
 
some
 
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
The CIR panel reports equivocal evidence that tocopherol may act as a tumor promoter.
 
some
 
Cosmetic Ingredient Review (CIR): CIR Assessments
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
The CIR panel reports that tocopherol was a dermal sensitizer in an animal study and contact allergy has been reported in human tests and case studies, although occurrence is rare.
 
some
 
Cosmetic Ingredient Review (CIR): CIR Assessments
Tocopherol functions as an antioxidant in personal care products.
 
low
 
Cosmetic Ingredient Review (CIR): CIR Assessments
Tocopherol was not genotoxic in in vitro tests with mammalian cells.
 
low
 
Cosmetic Ingredient Review (CIR): CIR Assessments
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
 
low
 
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
 
low
 
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
 
low
 
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: HYDROQUINONE
Suspected of causing genetic defects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Suspected of causing cancer
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
eye damage
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: HYDROQUINONE
Harmful if swallowed
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
confirmed animal carcinogen with unknown relevance to humans
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: HYDROQUINONE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: HYDROQUINONE
NTP Toxcast scored 1.5-2.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
Impurity: HYDROQUINONE
Not classifiable as to its carcinogenicity to humans
 
low
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: HYDROQUINONE
eye irritation
 
low
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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