|
May cause genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
May cause cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity (to females)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity (to males)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Reasonably Anticipated To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
|
European Union Ecolabel program data shows this substance has high acute toxicity to aquatic life
|
some
|
EU Ecolabel: Detergents Ingredients Database
|
|
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
|
some
|
Vanessa E. Melin, Travis E. Melin, Brian J. Dessify, Christina T. Nguyen, Caroline S. Shea & Terry C. Hrubec. 2015. Quaternary Ammonium Disinfectants Cause Subfertility in Mice by Targeting both Male and Female Reproductive Processes. Reproductive toxicology (Elmsford, N.Y.).
|
|
A peer-reviewed publication reports some quaternary ammonium compounds cause reproductive toxicity in animals.
|
some
|
Vanessa E. Melin, Haritha Potineni, Patricia Hunt, Jodi Griswold, Bill Siems, Stephen R. Werre & Terry C. Hrubec. 2014. Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70.
|
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes pulmonary edema
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes reproductive effects
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes leukemia
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes peritoneal cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Asthmagen (irritation)
|
some
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
|
Causes cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
liver damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
suspected human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Possibly carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
Quaternary ammonium compounds detected in human blood was associated with increased inflammation, decreased mitochondrial function and disruption of cholesterol.
|
some
|
Terry C. Hrubec, Ryan P. Seguin, Libin Xu, Gino A. Cortopassi, Sandipan Datta, Alexandra L. Hanlon, Alicia J. Lozano, Valerie A. McDonald, Claire A. Healy, Tyler C. Anderson, Najaha A. Musse & Richard T. Williams. 2021. Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure. Toxicology reports 8, 646-656.
|
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
This substance impacted cholesterol biosynthesis.
|
some
|
Josi Herron, Rosalyn C. Reese, Keri A. Tallman, Rohini Narayanaswamy, Ned A. Porter & Libin Xu. 2016. Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. Toxicological sciences : an official journal of the Society of Toxicology 151(2), 261-70.
|
|
Quaternary ammonium compounds altered neurodevelopment in cells.
|
some
|
Josi M. Herron, Hideaki Tomita, Collin C. White, Terrance J. Kavanagh & Libin Xu. 2021. Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment. Chemical research in toxicology 34(5), 1265-1274.
|
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
|
The European Union Ecolabel program reports this substance is readily biodegradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
The European Union Ecolabel program reports this substance is anaerobically degradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
