developmentb
D

CI 15850 (D&C RED NO. 6 OR 7) CALCIUM LAKE

 
This substance ranges from C to D depending on concentration/usage.
Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Low Concern
 
Developmental &
Reproductive Toxicity
 
No Data, Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of kidney and urinary effects; developmental/endocrine/reproductive effects; chronic aquatic toxicity
CI 15850 (D&C Red No. 6 or 7) Calcium Lake can be found in 1 product.
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Evidence

Health issue
 
Level of Concern
 
Source
A review article reports insufficient data to asssess gentoxicity of this substance, but related substances are genotoxic and/or carcinogenic.
 
some
 
P. Møller & H. Wallin. 2000. Genotoxic hazards of azo pigments and other colorants related to 1-phenylazo-2-hydroxynaphthalene. Mutation research 462(1), 13-30.
Caused mild skin irritation in animal tests.
 
some
 
Scientific Committee on Consumer Safety (SCCS). 2012. Opinion on Pigment Red 57, COLIPA n° C181. Oct-12 http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_112.pdf.
May cause or exacerbate dermatitis.
 
some
 
Gabsik Yang, Hye Eun Lee, Kyung-Min Lim, Yong-Kyu Choi, Kyu-Bong Kim, Byung-Mu Lee & Joo Young Lee. 2018. Potentiation of skin TSLP production by a cosmetic colorant leads to aggravation of dermatitis symptoms. Chemico-biological interactions 284, 41-47.
Caused mild eye irritation in animal tests.
 
low
 
Scientific Committee on Consumer Safety (SCCS). 2012. Opinion on Pigment Red 57, COLIPA n° C181. Oct-12 http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_112.pdf.
No sensitization observed in animal test.
 
low
 
Scientific Committee on Consumer Safety (SCCS). 2012. Opinion on Pigment Red 57, COLIPA n° C181. Oct-12 http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_112.pdf.
acute toxicity, oral LD50 (mg/kg)
 
low
 
Scientific Committee on Consumer Safety (SCCS). 2012. Opinion on Pigment Red 57, COLIPA n° C181. Oct-12 http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_112.pdf.
SCCS concludes this substance has no genotoxic potential.
 
low
 
Scientific Committee on Consumer Safety (SCCS). 2012. Opinion on Pigment Red 57, COLIPA n° C181. Oct-12 http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_112.pdf.

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: ANILINE
Suspected of causing genetic defects
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Suspected of causing cancer
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Causes damage to organs through prolonged or repeated exposure
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Very toxic to aquatic life
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Known to cause cancer
 
some
 
Proposition 65 List (2020 Update) - California OEHHA (Office of Environmental Health Hazard Assessment)
Impurity: CADMIUM
Suspected of causing genetic defects
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
May cause cancer
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Causes damage to organs through prolonged or repeated exposure
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Very toxic to aquatic life
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Very toxic to aquatic life with long lasting effects
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Fatal if inhaled
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Suspected of damaging fertility.
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Suspected of damaging the unborn child.
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
Carcinogenic to humans
 
some
 
Agents classified by the IARC Monographs (through Volume 127) - International Agency for Research on Cancer (IARC)
Impurity: CADMIUM
Known To Be Human Carcinogen
 
some
 
NTP 14th Report on Carcinogens - National Toxicology Program (NTP)
Impurity: ANILINE
Probably carcinogenic to humans
 
some
 
EPA Integrated Risk Information System (IRIS) - Cancer - Environmental Protection Agency (EPA)
Impurity: ANILINE
Probably carcinogenic to humans
 
some
 
Agents classified by the IARC Monographs (through Volume 127) - International Agency for Research on Cancer (IARC)
Impurity: CADMIUM
Probably carcinogenic to humans
 
some
 
EPA Integrated Risk Information System (IRIS) - Cancer - Environmental Protection Agency (EPA)
Impurity: ANILINE
Toxic if swallowed
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Toxic in contact with skin
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Toxic if inhaled
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: CADMIUM
kidney damage
 
some
 
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: CADMIUM
suspected human carcinogen
 
some
 
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: AROMATIC AMINES
Structurally related substances are classified as IARC Group 2B: possible human carcinogen (International Agency for Research on Carcinogens).
 
some
 
Agents classified by the IARC Monographs (through Volume 127) - International Agency for Research on Cancer (IARC)
Impurity: ANILINE
suspected of causing genetics defects
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
causes damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
confirmed animal carcinogen with unknown relevance to humans
 
some
 
Threshold Limit Value (TLV) Basis - American Conference of Governmental Industrial Hygienists (ACGIH)
Impurity: ANILINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
Toxic in contact with skin
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
toxic if inhaled
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
Toxic of swallowed
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: ANILINE
may cause damage to organs through prolonged or repeated exposure
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
may cause respiratory irritation
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
Causes skin irritation
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
Causes serious eye damage
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
causes serious eye irritation
Only in: Household Cleaners
 
some
 
GHS Data from ECHA Website - European Chemicals Agency (ECHA)
Impurity: ANILINE
Not classifiable as to its carcinogenicity to humans
 
low
 
Agents classified by the IARC Monographs (through Volume 127) - International Agency for Research on Cancer (IARC)
Impurity: ANILINE
EPA testing shows this substance has moderate acute toxicity to aquatic life
 
low
 
EPA Fathead Minnow Acute Toxicity Database - Environmental Protection Agency (EPA)
Impurity: ANILINE
EPA testing shows this substance has low acute toxicity to aquatic life
 
low
 
EPA Fathead Minnow Acute Toxicity Database - Environmental Protection Agency (EPA)
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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