Causes serious eye irritation
Only in: Household Cleaners

some

EU GHS Hazard Labeling Codes: GHS Hazard Codes

The European Commission's Scientific Committee on Consumer Safety reports this substance lacks data on contact allergy in humans.

low

EU Cosmetics Directive: Opinion on Frangrance allergens in cosmetics (2011)

In vitro testing in human cells found evidence of genotoxicity, but in vivo testing did not.

low

A. Lapczynski, S. Tsang, Y. Tokura, Y. Thakkar, G. Sullivan, I. G. Sipes, T. W. Schultz, D. Salvito, N. Sadekar, J. Romine, G. Ritacco, T. M. Penning, A. Patel, D. O'Brien, D. C. Liebler, A. M. Api, S. La Cava, K. Joshi, L. Jones, A. D. Fryer, M. Francis, C. Deodhar, W. Dekant, M. Date, M. L. Dagli, J. Buschmann, G. A. Burton, M. Bruze, D. Botelho & D. Belsito. 2019. RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS registry number 63500-71-0. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 130 Suppl 1, 110564.

Human and animal testing found no evidence of skin sensitization.

low

A. Lapczynski, S. Tsang, Y. Tokura, Y. Thakkar, G. Sullivan, I. G. Sipes, T. W. Schultz, D. Salvito, N. Sadekar, J. Romine, G. Ritacco, T. M. Penning, A. Patel, D. O'Brien, D. C. Liebler, A. M. Api, S. La Cava, K. Joshi, L. Jones, A. D. Fryer, M. Francis, C. Deodhar, W. Dekant, M. Date, M. L. Dagli, J. Buschmann, G. A. Burton, M. Bruze, D. Botelho & D. Belsito. 2019. RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS registry number 63500-71-0. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 130 Suppl 1, 110564.

Animal testing found no evidence of reproductive or developmental toxicity.

low

A. Lapczynski, S. Tsang, Y. Tokura, Y. Thakkar, G. Sullivan, I. G. Sipes, T. W. Schultz, D. Salvito, N. Sadekar, J. Romine, G. Ritacco, T. M. Penning, A. Patel, D. O'Brien, D. C. Liebler, A. M. Api, S. La Cava, K. Joshi, L. Jones, A. D. Fryer, M. Francis, C. Deodhar, W. Dekant, M. Date, M. L. Dagli, J. Buschmann, G. A. Burton, M. Bruze, D. Botelho & D. Belsito. 2019. RIFM fragrance ingredient safety assessment, 2-isobutyl-4-methyltetrahydro-2H-pyran-4-ol, CAS registry number 63500-71-0. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 130 Suppl 1, 110564.