Health issue
Level of Concern
Source
Harmful if swallowed
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Developmental effects reported in animal testing.
some
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
May cause an allergic skin reaction
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Dermal sensitization observed in a human study.
some
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
Dermal irritaition reported in human and animal studies.
some
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
Low acute oral toxicity
low
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
acute toxicity, oral LD50 (mg/kg)
low
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
Low acute dermal toxicity.
low
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
No evidence of mutagenicity in in vitro testing.
low
S. P. Bhatia, L. Jones, C. S. Letizia & A. M. Api. 2008. Fragrance material review on 4-tert-butylcyclohexyl acetate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 46 Suppl 12, S36-41.
The European Commission's Scientific Committee on Consumer Safety reports this substance shows negative results for causing contact allergy in humans.
low
EU Cosmetics Directive: Opinion on Frangrance allergens in cosmetics (2011)