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The National Toxicology Program concluded there is some evidence that this substance is carcinogenic based on animal testing.
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some
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William Eastin. 1991. NTP technical report on the toxicity studies of D&C Yellow No. 11 in F344/N Rats and B6C3F1 Mice (Feed Studies) (CAS No. 8003-22-3). Toxicity report series 8, 1-32.
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The National Toxicology Program reports evidence this substance may have developmental effects.
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some
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William Eastin. 1991. NTP technical report on the toxicity studies of D&C Yellow No. 11 in F344/N Rats and B6C3F1 Mice (Feed Studies) (CAS No. 8003-22-3). Toxicity report series 8, 1-32.
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A peer-reviewed study reports endocrine activity in cellular assays.
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some
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Patrick Tarnow, Catrin Zordick, Alex Bottke, Berit Fischer, Friederike Kühne, Tewes Tralau & Andreas Luch. 2020. Characterization of Quinoline Yellow Dyes As Transient Aryl Hydrocarbon Receptor Agonists. Chemical research in toxicology 33(3), 742-750.
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A peer-reviewed study reports evidence that this substance may interfere with DNA repair.
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some
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Farah Md Chequer, Vinicius P. Venancio, Mara R. Almeida, Alexandre F. Aissa, Maria Lourdes P. Bianchi & Lusânia Mg Antunes. 2017. Erythrosine B and quinoline yellow dyes regulate DNA repair gene expression in human HepG2 cells. Toxicology and industrial health 33(10), 765-774.
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A peer-reviewed study reports in vitro genotoxicity.
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some
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Farah Maria Drumond Chequer, Vinícius de Paula Venâncio, Maíra Rocha de Souza Prado, Luiz Raimundo Campos da Silva e Cunha Junior, Thiago Mescoloto Lizier, Maria Valnice Boldrin Zanoni, Rommel Rodríguez Burbano, Maria Lourdes Pires Bianchi & Lusânia Maria Greggi Antunes. 2015. The cosmetic dye quinoline yellow causes DNA damage in vitro. Mutation research. Genetic toxicology and environmental mutagenesis 777, 54-61.
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May cause an allergic skin reaction
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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May cause an allergic skin reaction
Only in: Household Cleaners
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some
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European Chemicals Agency (ECHA): GHS Data from ECHA Website
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A peer-reviewed study reports evidence of dermal sensitization from animal testing.
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some
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M. J. Palazzolo & L. C. DiPasquale. 1983. The sensitization potential of D & C Yellow No. 11 in guinea pigs. Contact dermatitis 9(5), 367-71.
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Allergic contact dermatitis reported in humans following occupational exposure.
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some
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K. Matsunaga, K. Hosokawa, M. Suzuki, Y. Arima & R. Hayakawa. 1988. Occupational allergic contact dermatitis in beauticians. Contact dermatitis 18(2), 94-6.
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A peer-reviewed article reports evidence of dermal sensitization from human testing.
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some
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S. Kita, T. Kobayashi, H. Kutsuna & A. M. Kligman. 1984. Human maximization testing of D&C Yellow no. 10 and Yellow no. 11. Contact dermatitis 11(4), 210-3.
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A peer-reviewed study reports of evidence of kidney and liver effects at high doses in animal testing.
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some
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W. C. Eastin, M. R. Elwell, S. Grumbein & J. H. Yuan. 1996. Effects of D&C yellow no. 11 ingestion on F344/N rats and B6C3F1 mice. Journal of toxicology and environmental health 48(2), 197-213.
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