developmentb
F

D&C BLACK NO. 2 (CI 77266)

 
Asthma/Respiratory
 
Some Concern
 
Skin Allergies &
Irritation
 
Low Concern
 
Developmental &
Reproductive Toxicity
 
No Data, Some Concern
 
Cancer
 
Moderate Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: Evidence of cancer; damage to DNA; respiratory effects
D&C Black No. 2 (CI 77266) can be found in 2 products.
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Evidence

Health issue
 
Level of Concern
 
Source
Known to cause cancer
 
high
 
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Known to cause cancer
 
high
 
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
SCCS concludes this substance impacts the immune system when inhaled.
 
moderate
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance may be carcinogenic when inhaled.
 
moderate
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
Possibly carcinogenic to humans
 
moderate
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Possibly carcinogenic to humans
 
moderate
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
confirmed animal carcinogen with unknown relevance to humans
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
confirmed animal carcinogen with unknown relevance to humans
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
SCCS concludes this substance may be genotoxic based on in vivo and in vitro evidence.
 
some
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance may be toxic to reproduction/development when inhaled.
 
some
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
bronchitis
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
bronchitis
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
A peer-reviewed study reports that maternal inhalation of this substance led to neurodevelopmental effects in offspring.
 
some
 
Masakazu Umezawa, Atsuto Onoda, Irina Korshunova, Alexander C. Ø Jensen, Ismo K. Koponen, Keld A. Jensen, Konstantin Khodosevich, Ulla Vogel & Karin S. Hougaard. 2018. Maternal inhalation of carbon black nanoparticles induces neurodevelopmental changes in mouse offspring. Particle and fibre toxicology 15(1), 36.
SCCS reports that inhalation of this substance impacted lung function in healthy humans.
 
some
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance is not an eye irritant.
 
low
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).
SCCS concludes this substance is not a skin irritant.
 
low
 
European Commission, Scientific Committee on Consumer Safety (SCCS). 2015. Opinion on Carbon Black (nano-form).

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: CADMIUM
Suspected of causing genetic defects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
May cause cancer
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Causes damage to organs through prolonged or repeated exposure
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Very toxic to aquatic life
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Very toxic to aquatic life with long lasting effects
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Fatal if inhaled
Only in: Household Cleaners
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging fertility.
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Suspected of damaging the unborn child.
 
some
 
EU GHS Hazard Labeling Codes: GHS Hazard Codes
Impurity: CADMIUM
Carcinogenic to humans
 
some
 
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: CADMIUM
Known To Be Human Carcinogen
 
some
 
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: CADMIUM
Probably carcinogenic to humans
 
some
 
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: CADMIUM
kidney damage
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
Impurity: CADMIUM
suspected human carcinogen
 
some
 
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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