developmentb
C

CI 45350 (D&C YELLOW NO. 7 OR 8)

 
Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
No Data, Some Concern
 
Developmental &
Reproductive Toxicity
 
Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
No Data, Some Concern
 
Top scoring factors: No information available on this substance.
CI 45350 (D&C Yellow No. 7 or 8) can be found in 1 product.
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Evidence

Health issue
 
Level of Concern
 
Source
A review article concludes this substance may be a develomental toxin based on evidence in humans and animals.
 
some
 
Raphael Alford, Haley M. Simpson, Josh Duberman, G. Craig Hill, Mikako Ogawa, Celeste Regino, Hisataka Kobayashi & Peter L. Choyke. 2009. Toxicity of organic fluorophores used in molecular imaging: literature review. Molecular imaging 8(6), 341-54.
NTP Toxcast scored 2.5-3.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
NTP Toxcast scored 2.5-3.5
 
some
 
National Toxicology Program (NTP): EWG Toxcast Analysis
A study by the National Toxicology Program reports this substance was genotoxic in vitro.
 
some
 
B. C. Myhr & W. J. Caspary. 1991. Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: results for 31 coded compounds in the National Toxicology Program. Environmental and molecular mutagenesis 18(1), 51-83.
A review article reports that adverse reactions to this substance have been reported in humans.
 
some
 
Ilyse S. Kornblau & Jaafar F. El-Annan. 1900. Adverse reactions to fluorescein angiography: A comprehensive review of the literature. Survey of ophthalmology 64(5), 679-693.
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
causes serious eye irritation
Only in: Household Cleaners
 
some
 
European Chemicals Agency (ECHA): GHS Data from ECHA Website
A peer-reviewed article reports that people with a history of drug allergy may have adverse reactions to this substance.
 
some
 
Zhaoan Su, Panpan Ye, Yan Teng, Lixia Zhang & Xiaohong Shu. 2012. Adverse reaction in patients with drug allergy history after simultaneous intravenous fundus fluorescein angiography and indocyanine green angiography. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 28(4), 410-3.
A peer-reviewed article reports that allergic reactions to this substance are observed in humans.
 
some
 
Dimitrios C. Kalogeromitros, Michael P. Makris, Xenophon S. Aggelides, Anagnostis I. Mellios, Fani C. Giannoula, Kyriaki A. Sideri, Alexander A. Rouvas & Panagiotis G. Theodossiadis. 2011. Allergy skin testing in predicting adverse reactions to fluorescein: a prospective clinical study. Acta ophthalmologica 89(5), 480-3.
Low acute oral toxicty.
 
low
 
Raphael Alford, Haley M. Simpson, Josh Duberman, G. Craig Hill, Mikako Ogawa, Celeste Regino, Hisataka Kobayashi & Peter L. Choyke. 2009. Toxicity of organic fluorophores used in molecular imaging: literature review. Molecular imaging 8(6), 341-54.
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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